The miniaturization trends on electronic components manufacturing, have challenged conventional knowledge on materials strength and deformation behavior. ”The smaller the stronger” has become a commonplace expression summarizing a multitude of experimental findings in micro-scale plasticity, and modelling tools capable of capturing this distinctive reality are in urgent demand. The thesis investigates the ubiquitous size effects in plastic deformation of micron-scale specimens. Tracing the source of such a behavior to the constituent elements of plastic deformation, we use as starting point the dynamics of discrete dislocations and try to embody them into a continuum framework. The thesis is structured in two independent parts. In t...