Aspects of cancer chemotherapy

A total of 107 cases (62 male and 45 female),with histologically proven malignant disease and all receiving cytotoxic therapy were studied.A brief review of the history of cancer chemotherapy is given > together with a detailed account of the principal agents currently available, methods and routes of administration, means of assessing response to treatment and the necessary routines of investigation.The results obtained are presented,mainly in tabular form. Assessment of response, incidence, severity, significance, mechanisms and management of toxic effects, the significance of hepatic metas¬ tases and causes of death in relation to oancer chemotherapy, are discussed in detail.Finally, the conclusions derived from the study of these cases are presented