The main parameters describing content and the accessibility of information from textbooks are many aspects such as text difficulty and others. Individual characteristics of pupils - that are represented by chosen student preconceptions and misconceptions - also belong to key factors. The providing of the comprehensive view of the issues regarding analysis and the linking of acquired pieces of knowledge with the practical textbook creation have been the main aims of this dissertation. The creation of an instructional text follows the analysis results of the topic carbohydrates and their metabolism in chosen textbooks and the preconception analysis of biochemical terms. The instructional text respects the results of the analysis. The theoret...