Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medicine. We present the first urinary metabolomics biomarker study of childhood aggression. We aim to examine the association of urinary metabolites and neurotransmitter ratios involved in key metabolic and neurotransmitter pathways in a large cohort of twins (N = 1,347) and clinic-referred children (N = 183) with an average age of 9.7 years. This study is part of ACTION (Aggression in Children: Unraveling gene-environment interplay to inform Treatment and InterventiON strategies), in which we developed a standardized protocol for large-scale collection of urine samples in children. Our analytical design consisted of three phases: a discovery phas...
In two studies the relationship between plasma monoamine metabolites and different parameters of agg...
DNA methylation profiles of aggressive behavior may capture lifetime cumulative effects of genetic, ...
Autism diagnosis is moving from the identification of common inherited genetic variants to a system...
Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medici...
Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medici...
Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medici...
This study introduces and illustrates the potential of an integrated multi-omics approach in investi...
Variation in metabolite levels reflects individual differences in genetic and environmental factors....
Variation in metabolite levels reflects individual differences in genetic and environmental factors....
Human aggression encompasses a wide range of behaviors and is related to many psychiatric disorders....
Human aggression encompasses a wide range of behaviors and is related to many psychiatric disorders....
Human aggression is a complex behaviour, the biological underpinnings of which remain poorly known. ...
This study introduces and illustrates the potential of an integrated multi-omics approach in investi...
Genòmica; Comportament humàGenómica; Comportamiento humanoGenomics; Human behaviourChildhood aggress...
Aggressive behavior exerts an enormous impact on society remaining among the main causes of worldwid...
In two studies the relationship between plasma monoamine metabolites and different parameters of agg...
DNA methylation profiles of aggressive behavior may capture lifetime cumulative effects of genetic, ...
Autism diagnosis is moving from the identification of common inherited genetic variants to a system...
Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medici...
Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medici...
Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medici...
This study introduces and illustrates the potential of an integrated multi-omics approach in investi...
Variation in metabolite levels reflects individual differences in genetic and environmental factors....
Variation in metabolite levels reflects individual differences in genetic and environmental factors....
Human aggression encompasses a wide range of behaviors and is related to many psychiatric disorders....
Human aggression encompasses a wide range of behaviors and is related to many psychiatric disorders....
Human aggression is a complex behaviour, the biological underpinnings of which remain poorly known. ...
This study introduces and illustrates the potential of an integrated multi-omics approach in investi...
Genòmica; Comportament humàGenómica; Comportamiento humanoGenomics; Human behaviourChildhood aggress...
Aggressive behavior exerts an enormous impact on society remaining among the main causes of worldwid...
In two studies the relationship between plasma monoamine metabolites and different parameters of agg...
DNA methylation profiles of aggressive behavior may capture lifetime cumulative effects of genetic, ...
Autism diagnosis is moving from the identification of common inherited genetic variants to a system...