Background: Serum biomarkers may inform and improve care in traumatic brain injury (TBI). We aimed to correlate serum biomarkers with clinical severity, care path and imaging abnormalities in TBI, and explore their incremental value over clinical characteristics in predicting computed tomographic (CT) abnormalities.Methods: We analyzed six serum biomarkers (S100B, NSE, GFAP, UCH-L1, NFL and t-tau) obtained <24 h post-injury from 2867 patients with any severity of TBI in the Collaborative European NeuroTrauma Effectiveness Research (CENTER-TBI) Core Study, a prospective, multicenter, cohort study. Univariable and multivariable logistic regression analyses were performed. Discrimination was assessed by the area under the receiver operating ch...
Blood biomarkers have been explored for their potential to provide objective measures in the assessm...
Glial fibrillary acidic protein (GFAP) is cleared by the Food and Drug Administration (FDA) to deter...
<div><p>Mild traumatic brain injury (TBI) accounts for the vast majority of the nearly two million b...
BACKGROUND: Serum biomarkers may inform and improve care in traumatic brain injury (TBI). We aimed t...
BackgroundSerum biomarkers may inform and improve care in traumatic brain injury (TBI). We aimed to ...
Background and Objectives: The annual global incidence of traumatic brain injury (TBI) is over 10 mi...
Blood biomarkers have been explored for their potential to provide objective measures in the assessm...
Blood biomarkers have been explored for their potential to provide objective measures in the assessm...
Abstract: Prognostication is challenging in patients with traumatic brain injury (TBI) in whom compu...
The aim of the study was to examine the ability of eight protein biomarkers and their combinations i...
BACKGROUND: Magnetic resonance imaging (MRI) carries prognostic importance after traumatic brain inj...
The aim of the study was to examine the ability of eight protein biomarkers and their combinations i...
Background: Several studies have reported an association between serum biomarker values and function...
Biomarkers are important for accurate diagnosis of complex disorders such as traumatic brain injury ...
Mild traumatic brain injury (mTBI) is a significant healthcare burden and its diagnosis remains a ch...
Blood biomarkers have been explored for their potential to provide objective measures in the assessm...
Glial fibrillary acidic protein (GFAP) is cleared by the Food and Drug Administration (FDA) to deter...
<div><p>Mild traumatic brain injury (TBI) accounts for the vast majority of the nearly two million b...
BACKGROUND: Serum biomarkers may inform and improve care in traumatic brain injury (TBI). We aimed t...
BackgroundSerum biomarkers may inform and improve care in traumatic brain injury (TBI). We aimed to ...
Background and Objectives: The annual global incidence of traumatic brain injury (TBI) is over 10 mi...
Blood biomarkers have been explored for their potential to provide objective measures in the assessm...
Blood biomarkers have been explored for their potential to provide objective measures in the assessm...
Abstract: Prognostication is challenging in patients with traumatic brain injury (TBI) in whom compu...
The aim of the study was to examine the ability of eight protein biomarkers and their combinations i...
BACKGROUND: Magnetic resonance imaging (MRI) carries prognostic importance after traumatic brain inj...
The aim of the study was to examine the ability of eight protein biomarkers and their combinations i...
Background: Several studies have reported an association between serum biomarker values and function...
Biomarkers are important for accurate diagnosis of complex disorders such as traumatic brain injury ...
Mild traumatic brain injury (mTBI) is a significant healthcare burden and its diagnosis remains a ch...
Blood biomarkers have been explored for their potential to provide objective measures in the assessm...
Glial fibrillary acidic protein (GFAP) is cleared by the Food and Drug Administration (FDA) to deter...
<div><p>Mild traumatic brain injury (TBI) accounts for the vast majority of the nearly two million b...