Matrix metalloproteinase 9 (MMP-9) expression is upregulated in vascular inflammation and participates in vascular remodeling, including aneurysm dilatation and arterial neointima development. Neointima at the arteriovenous (AV) fistula anastomosis site primarily causes AV fistula stenosis and failure; however, the effects of MMP-9 on perioperative AV fistula remodeling remain unknown. Therefore, we created AV fistulas (end-to-side anastomosis) in wild-type (WT) and MMP-9 knockout mice with chronic kidney disease to further clarify this. Neointima progressively developed in the AV fistula venous segment of WT mice during the four-week postoperative course, and MMP-9 knockout increased the lumen area and attenuated neointima size by reducing...
Hemodialysis is the most widely used option in chronic dialysis treatment and requires a suitable ...
Abdominal aortic aneurysm (AAA) is a complex multi-factorial disease leading to life-threatening com...
OBJECTIVE: We investigated the role of matrix metalloproteinase-8 (MMP8) in neointima formation and ...
Long-term success in vein grafting for bypassing arteries blocked by atherosclerosis is limited by m...
Hemodialysis vascular access can develop venous neointimal hyperplasia (VNH) causing stenosis. Recen...
Objective—Both matrix metalloproteinases (MMPs) and endothelial progenitor cells (EPCs) have been im...
<div><p>Hemodialysis vascular access can develop venous neointimal hyperplasia (VNH) causing stenosi...
ObjectiveMatrix metalloproteinase-9 (MMP-9) has been widely described to play a critical role in ane...
ObjectiveVenous dilatation and wall thickening are part of the maturation of an arteriovenous fistul...
Long-term success in vein grafting for bypassing arteries blocked by atherosclerosis is limited by m...
.Objectives: Injury stimulates smooth muscle cell SMC migration and proliferation by mechanisms that...
Objective-We investigated the role of matrix metalloproteinase-8 (MMP8) in neointima formation and i...
Thrombosed arteriovenous fistula for hemodialysis access is characterized by a marked inflammatory a...
Hemodialysis vascular access can develop venous neointimal hyperplasia (VNH) causing stenosis. Recen...
Background—Matrix metalloproteinase-9 (MMP-9) is involved in atherosclerosis and elevated MMP-9 acti...
Hemodialysis is the most widely used option in chronic dialysis treatment and requires a suitable ...
Abdominal aortic aneurysm (AAA) is a complex multi-factorial disease leading to life-threatening com...
OBJECTIVE: We investigated the role of matrix metalloproteinase-8 (MMP8) in neointima formation and ...
Long-term success in vein grafting for bypassing arteries blocked by atherosclerosis is limited by m...
Hemodialysis vascular access can develop venous neointimal hyperplasia (VNH) causing stenosis. Recen...
Objective—Both matrix metalloproteinases (MMPs) and endothelial progenitor cells (EPCs) have been im...
<div><p>Hemodialysis vascular access can develop venous neointimal hyperplasia (VNH) causing stenosi...
ObjectiveMatrix metalloproteinase-9 (MMP-9) has been widely described to play a critical role in ane...
ObjectiveVenous dilatation and wall thickening are part of the maturation of an arteriovenous fistul...
Long-term success in vein grafting for bypassing arteries blocked by atherosclerosis is limited by m...
.Objectives: Injury stimulates smooth muscle cell SMC migration and proliferation by mechanisms that...
Objective-We investigated the role of matrix metalloproteinase-8 (MMP8) in neointima formation and i...
Thrombosed arteriovenous fistula for hemodialysis access is characterized by a marked inflammatory a...
Hemodialysis vascular access can develop venous neointimal hyperplasia (VNH) causing stenosis. Recen...
Background—Matrix metalloproteinase-9 (MMP-9) is involved in atherosclerosis and elevated MMP-9 acti...
Hemodialysis is the most widely used option in chronic dialysis treatment and requires a suitable ...
Abdominal aortic aneurysm (AAA) is a complex multi-factorial disease leading to life-threatening com...
OBJECTIVE: We investigated the role of matrix metalloproteinase-8 (MMP8) in neointima formation and ...