Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta-analysis of European, North American and Australian cohorts
- Santos, S.
- Voerman, E.
- Amiano, P.
- Barros, H.
- Beilin, L. J.
- Bergström, A.
- Charles, M. A.
- Chatzi, L.
- Chevrier, C.
- Chrousos, G. P.
- Corpeleijn, E.
- Costa, O.
- Costet, N.
- Crozier, S.
- Devereux, G.
- Doyon, M.
- Eggesbø, M.
- Fantini, M. P.
- Farchi, S.
- Forastiere, F.
- Georgiu, V.
- Godfrey, K. M.
- Gori, D.
- Grote, V.
- Hanke, W.
- Hertz-Picciotto, I.
- Heude, B.
- Hivert, M. F.
- Hryhorczuk, D.
- Huang, R. C.
- Inskip, H.
- Karvonen, A. M.
- Kenny, L. C.
- Koletzko, B.
- Küpers, L. K.
- Lagström, H.
- Lehmann, I.
- Magnus, P.
- Majewska, R.
- Mäkelä, J.
- Manios, Y.
- McAuliffe, F. M.
- McDonald, S. W.
- Mehegan, J.
- Melén, E.
- Mommers, M.
- Morgen, C. S.
- Moschonis, G.
- Oostvogels, A. J.J.M.
- Vrijkotte, T. G.M.
DOIAbstract
Objective: To assess the separate and combined associations of maternal pre-pregnancy body mass index (BMI) and gestational weight gain with the risks of pregnancy complications and their population impact. Design: Individual participant data meta-analysis of 39 cohorts. Setting: Europe, North America, and Oceania. Population: 265 270 births. Methods: Information on maternal pre-pregnancy BMI, gestational weight gain, and pregnancy complications was obtained. Multilevel binary logistic regression models were used. Main outcome measures: Gestational hypertension, pre-eclampsia, gestational diabetes, preterm birth, small and large for gestational age at birth. Results: Higher maternal pre-pregnancy BMI and gestational weight gain were, across...
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