Screening to detect colorectal cancer (CRC) in an early or premalignant state is an effective method to reduce CRC mortality rates. Current stool-based screening tests, e.g. fecal immunochemical test (FIT), have a suboptimal sensitivity for colorectal adenomas and difficulty distinguishing adenomas at high risk of progressing to cancer from those at lower risk. We aimed to identify stool protein biomarker panels that can be used for the early detection of high-risk adenomas and CRC. Proteomics data (LC–MS/MS) were collected on stool samples from adenoma (n = 71) and CRC patients (n = 81) as well as controls (n = 129). Colorectal adenoma tissue samples were characterized by low-coverage whole-genome sequencing to determine their risk of prog...
BACKGROUND: Fecal immunochemical test (FIT) diagnostic accuracy for colorectal adenoma detection in ...
The majority of colorectal cancer (CRC) cases are preventable by early detection and removal of prec...
A non-invasive blood test that could reliably detect early CRC or large adenomas would provide an im...
Screening to detect colorectal cancer (CRC) in an early or premalignant state is an effective method...
Background: The fecal immunochemical test (FIT) for detecting hemoglobin is used widely for noninvas...
Background: The fecal immunochemical test (FIT) for detecting hemoglobin is used widely for noninvas...
Background: Colorectal cancer (CRC) is a major cause of cancer-related death worldwide. Cancer progr...
Colorectal cancer (CRC) is one of the deadliest cancers in the world. The early stage of the disease...
BACKGROUND: Accurate detection of characteristic proteins secreted by colon cancer tumor cells in bi...
Accurate detection of characteristic proteins secreted by colon cancer tumor cells in biological flu...
Background: accurate detection of characteristic proteins secreted by colon cancer tumor cells in bi...
Given the increasing incidence of colorectal cancer (CRC), performing new and cost-effective stool t...
Serological biomarkers may be an option for early detection of colorectal cancer (CRC). The present ...
Background. Colorectal cancer (CRC) is the second deadliest malignancy worldwide. This study aimed t...
Detecting and removing high-risk adenomas and early colorectal cancer (CRC) can reduce mortality of ...
BACKGROUND: Fecal immunochemical test (FIT) diagnostic accuracy for colorectal adenoma detection in ...
The majority of colorectal cancer (CRC) cases are preventable by early detection and removal of prec...
A non-invasive blood test that could reliably detect early CRC or large adenomas would provide an im...
Screening to detect colorectal cancer (CRC) in an early or premalignant state is an effective method...
Background: The fecal immunochemical test (FIT) for detecting hemoglobin is used widely for noninvas...
Background: The fecal immunochemical test (FIT) for detecting hemoglobin is used widely for noninvas...
Background: Colorectal cancer (CRC) is a major cause of cancer-related death worldwide. Cancer progr...
Colorectal cancer (CRC) is one of the deadliest cancers in the world. The early stage of the disease...
BACKGROUND: Accurate detection of characteristic proteins secreted by colon cancer tumor cells in bi...
Accurate detection of characteristic proteins secreted by colon cancer tumor cells in biological flu...
Background: accurate detection of characteristic proteins secreted by colon cancer tumor cells in bi...
Given the increasing incidence of colorectal cancer (CRC), performing new and cost-effective stool t...
Serological biomarkers may be an option for early detection of colorectal cancer (CRC). The present ...
Background. Colorectal cancer (CRC) is the second deadliest malignancy worldwide. This study aimed t...
Detecting and removing high-risk adenomas and early colorectal cancer (CRC) can reduce mortality of ...
BACKGROUND: Fecal immunochemical test (FIT) diagnostic accuracy for colorectal adenoma detection in ...
The majority of colorectal cancer (CRC) cases are preventable by early detection and removal of prec...
A non-invasive blood test that could reliably detect early CRC or large adenomas would provide an im...