The role of abdominal drainage in pancreatic resection - A multicenter validation study for early drain removal
- Linnemann, R. J. A.
- Patijn, G. A.
- van Rijssen, L. B.
- Besselink, M. G.
- Mungroop, T. H.
- de Hingh, I. H.
- Kazemier, G.
- Festen, S.
- de Jong, K. P.
- van Eijck, C. H. J.
- Scheepers, J. J. G.
- van der Kolk, M.
- den Dulk, M.
- Bosscha, K.
- Busch, O. R.
- Boerma, D.
- van der Harst, E.
- Nieuwenhuijs, V. B.
DOIAbstract
Background: Abdominal drainage and the timing of drain removal in patients undergoing pancreatic resection are under debate. Early drain removal after pancreatic resection has been reported to be safe with a low risk for clinical relevant postoperative pancreatic fistula (CR-POPF) when drain amylase on POD1 is 5000U/L the CR-POPF rate was 28%. When using a cut-off point of 2000U/L or 1000U/L during POD1-3, the CR-POPF rates were 6% and 5% respectively. For patients with an amylase level of >2000U/L and >1000UL during POD 1-3 the CR-POPF rates were 26% and 22% respectively (n = 223). Drain removal on POD4 or thereafter was associated with more complications (p = 0.004). Drain amylase level was shown to be the most statistically significant p...
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