Incidence of and risk factors for neighboring synchronous skin cancers during Mohs micrographic surgery: A prospective cohort study

Supplementary Material Supplemental eFigure 1. Example of study patient with synchronous skin cancers A) This patient presented for Mohs micrographic surgery (MMS) of a biopsy-proven BCC by the lateral canthus. The Mohs surgeon identified three synchronous lesions suspicious for skin cancer within 5 cm of the index lesion. Biopsies of all 3 synchronous lesions confirmed skin cancers. B) Synchronous lesion #1 (SCC in situ) was treated with shave and curettage. Lesions #2 and #3 (both invasive SCCs) were treated with MMS. C) The reconstruction of the index BCC was expanded to accommodate the defects of synchronous cancers #2 and #3. Supplemental eFigure 2. The Incidence of Synchronous Skin Cancers Increases with the Number of Risk Factors* *The four risk factors for synchronous skin cancer [see Supplemental eTable 1] are personal history of skin cancer, index lesion diagnosis of SCC, male gender, and age ≥65 years. Supplemental eTable 1: Clinicopathologic risk factors associated with neighboring synchronous skin cancer