Signal processing of quantitative continuous measurement of movements in the extremities

"A protocol for a low-cost quantitative continuous measurement of movements in the extremities of people with PD (McKay, et al., 2019) was administered to people with PD . . . and age- and sex-matched healthy control participants" (Harrigan, et al., Quantitative continuous measurement of movements in the extremities, 2020). "Healthy control participants were matched for age and sex with participants with PD. Participants with PD completed a single test session . . . , a test and a retest session . . . , or a test and two retest sessions . . . . HC participants completed test and retest sessions " (Harrigan, et al., Quantitative continuous measurement of movements in the extremities, 2020). Thirty-two trained raters who were certified in the Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) (Goetz, et al., 2008) were presented the output of the ten participants with PD who completed a single test session (Pilot Test and Retest). Raters were presented two sets of 40 quizzes containing five representations for scoring of (A) output signals and FFTs and (B) CWTs (Pilot Test and Retest). Each quiz contained the panels of the x, y, and z representations of the finger and wrist or the toe and ankle of the five repetitive tasks. Each panel to be scored included six images corresponding to the signals of the three dimensions of the two accelerometers on a single extremity. The laterality of the representations was not stated. Raters were presented five sets of six images of the original signal and the fast Fourier transform (FFT) or the continuous wavelet transforms (CWTs). Raters were presented either five panels of output signals and FFTs or CWTs. Panels did not include output signals and FFTs and CWTs simultaneously. Raters were instructed to score (A) output signals and FFTs and (B) CWTs analogously to the clinical coding forms as indicated the the instructions in the data. The raters also completed the output of the ten participants with PD and eight HCs who completed a two test session (CWT Test and Retest). Raters were presented two sets of 72 quizzes containing five representations for scoring of (CWTs (Pilot Test and Retest). Each quiz contained the panels of averaged signals of the x, y, and z representations of the finger and wrist or the toe and ankle of the five repetitive tasks. Each panel to be scored included two images corresponding to the signals of the three dimensions of the two accelerometers on a single extremity. The laterality of the representations was not stated. Raters were asked to complete ratings independently at convenient times during the week