Parasitic myoma after laparoscopic morcellation: a systematic review of the literature

Laparoscopic morcellation is frequently used for tissue removal after laparoscopic hysterectomy or myomectomy and may result in parasitic myomas, due to seeding of remained tissue fragments in the abdominal cavity. However, little is known about the incidence and risk factors of this phenomenon.To identify the incidence and risk factors for the development of parasitic myoma after laparoscopic morcellation.A systematic review of the literature in Pubmed (MEDLINE) and Embase was conducted. Reference lists of identified relevant articles were checked for missing case reports.Studies reporting on incidence or cases of parasitic myoma diagnosed after laparoscopic morcellation were selected. Studies were excluded when history of laparoscopic morcellation was lacking or final pathology demonstrated a malignancy or endometriosis.Data were extracted and analysed on incidence of parasitic myomas and characteristics of case reports.Fourty-four studies were included. Sixty-nine women diagnosed with parasitic myomas after laparoscopic morcellation were identified. Mean age was 40.8 (?7.5) years (range 24-57), median time between surgery and diagnosis was 48.0?months (range 1-192) and mean number of parasitic myomas was 2.9 (?3.3) (range 1-16). The overall incidence of parasitic myomas after laparoscopic morcellation was 0.12-0.95%.Although the incidence is relatively low, it is important to discuss the risk of parasitic myoma after laparoscopic morcellation with women and balance towards alternative treatment options. The duration of steroid exposure after laparoscopic morcellation might be a risk factor for development of parasitic myomas.Systematic review on the incidence and risk factors for parasitic myoma after laparoscopic morcellation.? 2015 Royal College of Obstetricians and Gynaecologists