Obesity has a serious effect on human health. It relates to metabolic syndrome, including the associated disorders such as type 2 diabetes, heart disease, stroke and hyperemia. The peroxisome proliferator-activated receptors (PPARs) are important receptors to control fat metabolism in the human body. Because of the safety concerns of synthetic drugs targeting PPARs, ligands from natural sources have drawn interest. Earlier, we have found high PPAR activities in extracts from Agaricus bisporus (white button mushroom, WBM). WBM contains a wide range of candidate compounds which could be agonists of PPARs. To identify which compounds are responsible for PPAR activation by WBM extracts, we used fractionation coupled to effect-directed analysis ...
<div><p>Dyslipidemia is a major risk factor for development of several obesity-related diseases. The...
International audiencePeroxisome proliferator-activated receptor gamma (PPARγ) is a key regulator of...
BACKGROUND: The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcripti...
Obesity has a serious effect on human health. It relates to metabolic syndrome, including the associ...
Obesity is a major health problem in the world, and it relates to type2-diabetes, heart disease and ...
Peroxisome proliferator-activated receptors (PPARs) are transcription factors whose isoforms (α, β/δ...
The peroxisome proliferator-activated receptors (PPARα,γ,β) are important druggable targets to treat...
Obesity is a major health concern for a growing fraction of the population, with the prevalence of o...
Obesity is a major health concern for a growing fraction of the population, with the prevalence of o...
<div><h3>Background</h3><p>Natural extracts have played an important role in the prevention and trea...
[[abstract]]Bitter gourd ( Momordica charantia L.) is a common vegetable in Asia that has been used ...
Peroxisome Proliferator Activated Receptors (PPARs) α, -γ and -β/δ are ligand-activated transcriptio...
BACKGROUND: Natural extracts have played an important role in the prevention and treatment of diseas...
AbstractAgonists of the nuclear receptor PPARγ are therapeutically used to combat hyperglycaemia ass...
The prevalence of obesity and its associated comorbidities has grown to epidemic proportions in the ...
<div><p>Dyslipidemia is a major risk factor for development of several obesity-related diseases. The...
International audiencePeroxisome proliferator-activated receptor gamma (PPARγ) is a key regulator of...
BACKGROUND: The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcripti...
Obesity has a serious effect on human health. It relates to metabolic syndrome, including the associ...
Obesity is a major health problem in the world, and it relates to type2-diabetes, heart disease and ...
Peroxisome proliferator-activated receptors (PPARs) are transcription factors whose isoforms (α, β/δ...
The peroxisome proliferator-activated receptors (PPARα,γ,β) are important druggable targets to treat...
Obesity is a major health concern for a growing fraction of the population, with the prevalence of o...
Obesity is a major health concern for a growing fraction of the population, with the prevalence of o...
<div><h3>Background</h3><p>Natural extracts have played an important role in the prevention and trea...
[[abstract]]Bitter gourd ( Momordica charantia L.) is a common vegetable in Asia that has been used ...
Peroxisome Proliferator Activated Receptors (PPARs) α, -γ and -β/δ are ligand-activated transcriptio...
BACKGROUND: Natural extracts have played an important role in the prevention and treatment of diseas...
AbstractAgonists of the nuclear receptor PPARγ are therapeutically used to combat hyperglycaemia ass...
The prevalence of obesity and its associated comorbidities has grown to epidemic proportions in the ...
<div><p>Dyslipidemia is a major risk factor for development of several obesity-related diseases. The...
International audiencePeroxisome proliferator-activated receptor gamma (PPARγ) is a key regulator of...
BACKGROUND: The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcripti...