Changes in Coronary Plaque Volume: Comparison of Serial Measurements on Intravascular Ultrasound and Coronary Computed Tomographic Angiography
- Nakanishi, R.
- Alani, A.
- Matsumoto, S.
- Li, D.
- Fahmy, M.
- Abraham, J.
- Dailing, C.
- Broersen, A.
- Kitslaar, P.H.
- Nasir, K.
- Min, J.K.
- Budoff, M.J.
DOIAbstract
Serial measurements of coronary plaque volume have been used to evaluate drug efficacy in atherosclerotic progression. However, the usefulness of computed tomography for this purpose is unknown. We investigated whether the change in total plaque volume on coronary computed tomographic angiography is associated with the change in segment plaque volume on intravascular ultrasound.We prospectively enrolled 11 consecutive patients (mean age, 56.3 +/- 5 yr; 6 men) who were to undergo serial invasive coronary angiographic examinations with use of grayscale intravascular ultrasound and coronary computed tomography, performed <180 days apart at baseline and from 1 to 2 years later. Subjects underwent 186 serial measurements of total plaque volume o...
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