Add to ORKGThe thesis discussed several strategies that may contribute to further CVD risk reduction in the future. We described two novel lipid-lowering strategies, we unraveled (part of) the etiology of the cardiovascular safety issues of TKIs that are used for the treatment of CML, and we investigated the dose effects of PFOA on lipoprotein metabolism. Looking forward, we developed a novel mouse model that can be used for the study of diabetic macrovascular complications, and we evaluated the potential of OSM as novel target in CVD.</table
Motivation:Atherosclerosis is a complex multi-pathway inflammatory disease where accumulation of oxi...
Atherosclerosis is one of the primary causes of cardiovascular disease and mortality. This chronic i...
Hyperlipidemia is the most important risk factor for atherosclerosis, which is the major cause of ca...
The main cause of cardiovascular disease (CVD) is atherosclerosis. Several genes that affect atheros...
Aims: This study aimed to investigate systematically (i) the appropriate dietary conditions to induc...
Although cardiovascular disease (CVD) is the leading cause of morbimortality worldwide, promising ne...
Atherosclerosis is a multifactorial highly-complex disease with numerous etiologies that work synerg...
Empirical thesis.Includes bibliographical references.Chapter 1. Introduction -- Chapter 2. Literatur...
Cardiovascular disease (CVD) is a major cause of mortality and morbidity in the Western world. CVD i...
Atherosclerosis is a multifactorial and complex disorder. This thesis focusses on three of the major...
Atherosclerosis is a progressive disease of the large arteries characterized by lipid deposition, in...
The reduction of plasma apolipoprotein B (apoB)containing lipoproteins has long been pursued as the ...
Although significant evidence supports the concept that low high density lipoprotein cholesterol (HD...
BACKGROUND: Causes and consequences of the complex changes in lipids occurring in the metabolic s...
Cardiovascular disease is the number one cause of death worldwide. The most important risk factor fo...
Motivation:Atherosclerosis is a complex multi-pathway inflammatory disease where accumulation of oxi...
Atherosclerosis is one of the primary causes of cardiovascular disease and mortality. This chronic i...
Hyperlipidemia is the most important risk factor for atherosclerosis, which is the major cause of ca...
The main cause of cardiovascular disease (CVD) is atherosclerosis. Several genes that affect atheros...
Aims: This study aimed to investigate systematically (i) the appropriate dietary conditions to induc...
Although cardiovascular disease (CVD) is the leading cause of morbimortality worldwide, promising ne...
Atherosclerosis is a multifactorial highly-complex disease with numerous etiologies that work synerg...
Empirical thesis.Includes bibliographical references.Chapter 1. Introduction -- Chapter 2. Literatur...
Cardiovascular disease (CVD) is a major cause of mortality and morbidity in the Western world. CVD i...
Atherosclerosis is a multifactorial and complex disorder. This thesis focusses on three of the major...
Atherosclerosis is a progressive disease of the large arteries characterized by lipid deposition, in...
The reduction of plasma apolipoprotein B (apoB)containing lipoproteins has long been pursued as the ...
Although significant evidence supports the concept that low high density lipoprotein cholesterol (HD...
BACKGROUND: Causes and consequences of the complex changes in lipids occurring in the metabolic s...
Cardiovascular disease is the number one cause of death worldwide. The most important risk factor fo...
Motivation:Atherosclerosis is a complex multi-pathway inflammatory disease where accumulation of oxi...
Atherosclerosis is one of the primary causes of cardiovascular disease and mortality. This chronic i...
Hyperlipidemia is the most important risk factor for atherosclerosis, which is the major cause of ca...