Candida albicans causes systemic life-threatening infections, particularly in immunocompromised individuals, such as patients in intensive care units, patients undergoing chemotherapy, and post-surgical and neutropenic patients. The proliferation of invading Candida cells is mainly limited by the action of the human innate immune system, in which phagocytic cells play a fundamental role. This function is, however, limited in neutropenic patients, who rely mainly on the protective immunity mediated by macrophages. Macrophages have been shown to release extracellular DNA fibers, known as macrophage extracellular traps (METs), which can entrap and kill various microbes by a process called ETosis. In this study, we observed that, upon contact w...
The fungal pathogen Candida albicans causes macrophage death and escapes, but the molecular mechanis...
Macrophages, cells effective in sensing, internalizing and killing Candida albicans, are intertwined...
The ability of Candiada albicans to convert from yeast to hyphal form enhances the ability of this o...
The innate immune system is the first defense against invasive fungal infections, including those ca...
The innate immune system is the first line of defense against invasive fungal infections. As a conse...
The innate immune system is the first line of defense against invasive fungal infections. As a conse...
The innate immune system is the first line of defense against invasive fungal infections. As a conse...
AbstractThe pathogenicity of the opportunistic human fungal pathogen Candida albicans depends on its...
ABSTRACT The innate immune system is the first line of defense against invasive fungal infections. A...
Autophagy is used by eukaryotes in bulk cellular material recycling and in immunity to intracellular...
Autophagy is used by eukaryotes in bulk cellular material recycling and in immunity to intracellular...
Autophagy is used by eukaryotes in bulk cellular material recycling and in immunity to intracellular...
AbstractCandida albicans is an opportunistic pathogen and is recognised and phagocytosed by macropha...
The formation of extracellular traps (ETs) has recently been recognized as a novel defense mechanism...
Macrophages, cells effective in sensing, internalizing and killing Candida albicans, are intertwined...
The fungal pathogen Candida albicans causes macrophage death and escapes, but the molecular mechanis...
Macrophages, cells effective in sensing, internalizing and killing Candida albicans, are intertwined...
The ability of Candiada albicans to convert from yeast to hyphal form enhances the ability of this o...
The innate immune system is the first defense against invasive fungal infections, including those ca...
The innate immune system is the first line of defense against invasive fungal infections. As a conse...
The innate immune system is the first line of defense against invasive fungal infections. As a conse...
The innate immune system is the first line of defense against invasive fungal infections. As a conse...
AbstractThe pathogenicity of the opportunistic human fungal pathogen Candida albicans depends on its...
ABSTRACT The innate immune system is the first line of defense against invasive fungal infections. A...
Autophagy is used by eukaryotes in bulk cellular material recycling and in immunity to intracellular...
Autophagy is used by eukaryotes in bulk cellular material recycling and in immunity to intracellular...
Autophagy is used by eukaryotes in bulk cellular material recycling and in immunity to intracellular...
AbstractCandida albicans is an opportunistic pathogen and is recognised and phagocytosed by macropha...
The formation of extracellular traps (ETs) has recently been recognized as a novel defense mechanism...
Macrophages, cells effective in sensing, internalizing and killing Candida albicans, are intertwined...
The fungal pathogen Candida albicans causes macrophage death and escapes, but the molecular mechanis...
Macrophages, cells effective in sensing, internalizing and killing Candida albicans, are intertwined...
The ability of Candiada albicans to convert from yeast to hyphal form enhances the ability of this o...