Add to ORKGGrowing evidence suggests that epigenetic mechanisms like microRNA-mediated transcriptional regulation contribute to the pathogenesis of parkinsonism. In order to study the influence of microRNAs (miRNAs), we analyzed the miRNome 2 days prior to major cell death in α-synuclein-overexpressing Lund human mesencephalic neurons, a well-established cell model of Parkinson\u27s disease (PD), by next-generation sequencing. The expression levels of 23 miRNAs were significantly altered in α-synuclein-overexpressing cells, 11 were down- and 12 upregulated
Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Its neuropathological...
Parkinson\u27s disease (PD) is a prevalent neurodegenerative disorder with pathological features inc...
Parkinson’s disease (PD) is a neurodegenerative synucleinopathy that has a not yet fully understood ...
The presence of α-synuclein aggregates in the characteristic Lewy body pathology seen in idiopathic ...
miRNAs were recently implicated in the pathogenesis of numerous diseases, including neurological dis...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
Synaptic dysfunction is an early alteration in multiple neurodegenerative disorders. Parkinson’s d...
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder with pathological features includ...
<div><p>Parkinson’s disease (PD) is a prevalent neurodegenerative disorder with pathological feature...
miRNAs were recently implicated in the pathogenesis of numerous diseases, including neurological dis...
Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Its neuropathological...
Parkinson\u27s disease (PD) is a prevalent neurodegenerative disorder with pathological features inc...
Parkinson’s disease (PD) is a neurodegenerative synucleinopathy that has a not yet fully understood ...
The presence of α-synuclein aggregates in the characteristic Lewy body pathology seen in idiopathic ...
miRNAs were recently implicated in the pathogenesis of numerous diseases, including neurological dis...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s di...
Synaptic dysfunction is an early alteration in multiple neurodegenerative disorders. Parkinson’s d...
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder with pathological features includ...
<div><p>Parkinson’s disease (PD) is a prevalent neurodegenerative disorder with pathological feature...
miRNAs were recently implicated in the pathogenesis of numerous diseases, including neurological dis...
Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Its neuropathological...
Parkinson\u27s disease (PD) is a prevalent neurodegenerative disorder with pathological features inc...
Parkinson’s disease (PD) is a neurodegenerative synucleinopathy that has a not yet fully understood ...