CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCell signaling mediated by P2X7 receptors (P2X7R) has been suggested to be involved in epileptogenesis, via modulation of intracellular calcium levels, excitotoxicity, activation of inflammatory cascades, and cell death, among other mechanisms. These proc134467478CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPAR...
Epilepsy is one of the most common chronic diseases of the central nervous system (CNS). Treatment o...
Abstract Background and purpose: Refractory status epilepticus is a clinical emergency associated w...
AIMS: Early-life seizures, particularly when prolonged, may be harmful to the brain. Current pharmac...
The ATP-gated ionotropic P2X7 receptor (P2X7R) modulates glial activation, cytokine production and n...
Although ATP and P2X receptor activity have been lately associated with epilepsy, little is known re...
The P2X7 receptor is an ATP-gated non-selective cation-permeable ionotropic receptor selectively exp...
Epilepsy is a common and disabling neurologic disease characterized by the occurrence of recurrent, ...
Prolonged seizures are amongst the most common neurological emergencies. Status epilepticus is a sta...
Neuroinflammation is thought to contribute to the pathogenesis and maintenance of temporal lobe epil...
Current pharmacological approaches to treat epilepsy are mainly focused on enhancing neuronal inhibi...
Abstract Background The release of tumor necrosis factor-α (TNF-α) appears depend on the P2X7 recept...
The ionotropic ATP-gated P2X7 receptor is an important contributor to inflammatory signaling cascade...
Despite the progress made in the development of new antiepileptic drugs (AEDs), the biggest challeng...
Epilepsy is a common and devastating neurological disorder characterised by increased and abnormal n...
Thirty percent of the adult population with epilepsy is resistant to commercially available anti-sei...
Epilepsy is one of the most common chronic diseases of the central nervous system (CNS). Treatment o...
Abstract Background and purpose: Refractory status epilepticus is a clinical emergency associated w...
AIMS: Early-life seizures, particularly when prolonged, may be harmful to the brain. Current pharmac...
The ATP-gated ionotropic P2X7 receptor (P2X7R) modulates glial activation, cytokine production and n...
Although ATP and P2X receptor activity have been lately associated with epilepsy, little is known re...
The P2X7 receptor is an ATP-gated non-selective cation-permeable ionotropic receptor selectively exp...
Epilepsy is a common and disabling neurologic disease characterized by the occurrence of recurrent, ...
Prolonged seizures are amongst the most common neurological emergencies. Status epilepticus is a sta...
Neuroinflammation is thought to contribute to the pathogenesis and maintenance of temporal lobe epil...
Current pharmacological approaches to treat epilepsy are mainly focused on enhancing neuronal inhibi...
Abstract Background The release of tumor necrosis factor-α (TNF-α) appears depend on the P2X7 recept...
The ionotropic ATP-gated P2X7 receptor is an important contributor to inflammatory signaling cascade...
Despite the progress made in the development of new antiepileptic drugs (AEDs), the biggest challeng...
Epilepsy is a common and devastating neurological disorder characterised by increased and abnormal n...
Thirty percent of the adult population with epilepsy is resistant to commercially available anti-sei...
Epilepsy is one of the most common chronic diseases of the central nervous system (CNS). Treatment o...
Abstract Background and purpose: Refractory status epilepticus is a clinical emergency associated w...
AIMS: Early-life seizures, particularly when prolonged, may be harmful to the brain. Current pharmac...