15siProline-rich antimicrobial peptides (PR-AMPs) having a potent antimicrobial activity predominantly toward Gram-negative bacteria and negligible toxicity toward host cells, are attracting attention as new templates for developing antibiotic drugs. We have previously isolated and characterized several bactenecins that are promising in this respect, from the leukocytes of the domestic goat Capra hircus: ChBac5, miniChBac7.5N-α, and -β, as well as ChBac3.4. Unlike the others, ChBac3.4 shows a somewhat unusual pattern of activities for a mammalian PR-AMP: it is more active against bacterial membranes as well as tumor and, to the lesser extent, normal cells. Here we describe a SAR study of ChBac3.4 (RFRLPFRRPPIRIHPPPFYPPFRRFL-NH2) which eluci...
Cytotoxic effect of the antimicrobial peptide ChMAP-28 from leucocytes of the goat Capra hircus was ...
Bactenecin (Bac) 5 is a bovine antimicrobial peptide (AMP) capable of killing some species of bacter...
Antimicrobial peptides (AMP), part of the innate immune system, are well studied for their ability t...
Resistance of pathogenic microorganisms to conventional antibiotics is growing rapidly in recent yea...
We isolated a new proline-rich peptide, ChBac3.4, from leukocytes of the goat (Capra hirca) and dete...
Bactenecin is a 12-amino acid-long cyclic peptide from bovine neutrophils. It has the sequence: RLC...
Antimicrobial peptides (AMP), part of the innate immune system, are well studied for their ability t...
Antimicrobial peptides (AMP), part of the innate immune system, are well studied for their ability t...
Being essential components of innate immune system, animal antimicrobial peptides (AMPs) also known ...
Cytotoxic effect of the antimicrobial peptide ChMAP-28 from leucocytes of the goat Capra hircus was ...
Cytotoxic effect of the antimicrobial peptide ChMAP-28 from leucocytes of the goat Capra hircus was ...
Being essential components of innate immune system, animal antimicrobial peptides (AMPs) also known ...
Cytotoxic effect of the antimicrobial peptide ChMAP-28 from leucocytes of the goat Capra hircus was ...
A series of shorter synthetic peptides analogues of ovine bactenecin 5 (OaBac5), Phe-Arg-Pro-Xaa (Xa...
Endogenous antimicrobial peptides of the cathelicidin family contribute to innate immunity. The emer...
Cytotoxic effect of the antimicrobial peptide ChMAP-28 from leucocytes of the goat Capra hircus was ...
Bactenecin (Bac) 5 is a bovine antimicrobial peptide (AMP) capable of killing some species of bacter...
Antimicrobial peptides (AMP), part of the innate immune system, are well studied for their ability t...
Resistance of pathogenic microorganisms to conventional antibiotics is growing rapidly in recent yea...
We isolated a new proline-rich peptide, ChBac3.4, from leukocytes of the goat (Capra hirca) and dete...
Bactenecin is a 12-amino acid-long cyclic peptide from bovine neutrophils. It has the sequence: RLC...
Antimicrobial peptides (AMP), part of the innate immune system, are well studied for their ability t...
Antimicrobial peptides (AMP), part of the innate immune system, are well studied for their ability t...
Being essential components of innate immune system, animal antimicrobial peptides (AMPs) also known ...
Cytotoxic effect of the antimicrobial peptide ChMAP-28 from leucocytes of the goat Capra hircus was ...
Cytotoxic effect of the antimicrobial peptide ChMAP-28 from leucocytes of the goat Capra hircus was ...
Being essential components of innate immune system, animal antimicrobial peptides (AMPs) also known ...
Cytotoxic effect of the antimicrobial peptide ChMAP-28 from leucocytes of the goat Capra hircus was ...
A series of shorter synthetic peptides analogues of ovine bactenecin 5 (OaBac5), Phe-Arg-Pro-Xaa (Xa...
Endogenous antimicrobial peptides of the cathelicidin family contribute to innate immunity. The emer...
Cytotoxic effect of the antimicrobial peptide ChMAP-28 from leucocytes of the goat Capra hircus was ...
Bactenecin (Bac) 5 is a bovine antimicrobial peptide (AMP) capable of killing some species of bacter...
Antimicrobial peptides (AMP), part of the innate immune system, are well studied for their ability t...