12noA number of studies have evaluated the role of IGF-I measurement in the diagnosis of growth hormone deficiency (GHD). This study aimed to evaluate the accuracy and the best cut-off of IGF-I SDS in the diagnosis of GHD in a large cohort of short children and adolescents. One-hundred and forty-two children and adolescents with GHD [(63 organic/genetic (OGHD), 79 idiopathic (IGHD)] and 658 short non-GHD children (median age 10.4 y) were included in the analysis. The two groups were subdivided according to age (G1 <6, G2 6<9, G3 9<12, G4 ≥12) and to pubertal status. Serum IGF-I was measured by the same chemiluminescence assay in all samples and expressed as age and sex-based SDS. Receiver operating characteristic (ROC) analysis was used to ...
Background: The analysis of insulin-like growth factor I (IGF-I) is an important tool for pediatrici...
The diagnosis of GH deficiency (GHD) is based on the measurement of peak GH responses to pharmacol...
The IGF1 generation test (IGFGT) is often used during the assessment of suspected GH insensitivity (...
A number of studies have evaluated the role of IGF1 measurement in the diagnosis of growth hormone d...
The diagnosis of childhood-onset growth hormone (GH) deficiency (GHD) is not straightforward, requir...
The diagnosis of GH deficiency (GHD) is based on the measurement of peak GH responses to pharmacolog...
The diagnosis of GH deficiency (GHD) is based on the measurement of peak GH responses to pharmacolog...
The diagnosis of GH deficiency (GHD) is based on the measurement of peak GH responses to pharmacolog...
The diagnosis of growth hormone (GH) deficiency (GHD) in childhood is not straightforward, being sti...
Background: The analysis of insulin-like growth factor I (IGF-I) is an important tool for pediatrici...
The diagnosis of GH deficiency (GHD) is based on the measurement of peak GH responses to pharmacol...
The IGF1 generation test (IGFGT) is often used during the assessment of suspected GH insensitivity (...
A number of studies have evaluated the role of IGF1 measurement in the diagnosis of growth hormone d...
The diagnosis of childhood-onset growth hormone (GH) deficiency (GHD) is not straightforward, requir...
The diagnosis of GH deficiency (GHD) is based on the measurement of peak GH responses to pharmacolog...
The diagnosis of GH deficiency (GHD) is based on the measurement of peak GH responses to pharmacolog...
The diagnosis of GH deficiency (GHD) is based on the measurement of peak GH responses to pharmacolog...
The diagnosis of growth hormone (GH) deficiency (GHD) in childhood is not straightforward, being sti...
Background: The analysis of insulin-like growth factor I (IGF-I) is an important tool for pediatrici...
The diagnosis of GH deficiency (GHD) is based on the measurement of peak GH responses to pharmacol...
The IGF1 generation test (IGFGT) is often used during the assessment of suspected GH insensitivity (...