Can neutrophil lymphocyte ratio be a marker in stage 1 testicular tumor occult metastasis parameters?

Objective: Neutrophile-Lymphocyte (NLR) and Platelet-Lymphocyte ratio (PLR)comparison is an easy to use and cost-effective method in diagnosis of some cancersand diseases. In this study, we aimed to investigate if NLR/PLR ratio evaluation couldbe utilized in diagnosis of testicular malignencies especially in early-term with occultmetastasis.Materials and methods: A total of 40 patients at stage-I, who have undergone radicalinguinal orchiectomy intervention for testicular tumor between 2015 and 2019, and 43control individuals without any testicular complaints were included in this retrospectivestudy. The relationship between pathological risk factors for occult metastatic disease inStage-I testicular cancer and NLR/PLR values were investigated.Results: The average age was 30.05 years, and there was no significant differencebetween the groups by means of age (p=0.150). The NLR and PLR values of the tumorgroup were prominently higher in the patient group, when compared with the controlgroup (p=0.001 and p=0.016, respectively). In the correlation analysis between riskfactors for occult metastatic disease in Stage-I testicular cancer and NLR/PLR, we havefound that only a significant correlation was present in terms of tumor size.Conclusion: As a result, we have concluded that NLR increases in all types oftesticular tumors. We suggest that higher NLR ratio values can be used as prognosticmarker in clinical practice.Key words: Testicular tumor, occult metastasis, neutrophil/lymphocyte ratio,platelet/lymphocyte ratio.