The Efficacy Of Intralesional Steroid Injection in The Treatment Of Corrosive Esophageal Strictures in Children

ABSTRACTBackground: In the treatment of serious corrosive esophageal strictures, esophageal dilatation may be inadequate. The purpose of this study was to evaluate the effectiveness of intralesional steroid injection as an adjunct to dilatation therapy. Methods: This is a clinical trial study, which was conducted on 42 patients with corrosive esophageal stricture. The patients were admitted to pediatric endoscopic department at Zagazig University Hospitals. They were randomly divided into 2 groups. Group I/ control included 21 patients (10 males and 11 females; mean age 28±20.8 months), they received dilatation therapy only and Group II/ study included 21 patients (13 males and 8 females; mean age 40.4± 20.5 months), they received an additional treatment by 1ml intralesional steroid injection of triamcinolone actenoid in the strict part. Results: Number of dilatation therapy, dysphagia and vomiting were highly statistically significantly decreased in study group vs control group. At the end of the follow-up period, 30% of control group improved while 85% of the study group improved. Conclusions: The findings of the current study support the use of intralesional triamcinolone in corrosive esoghageal stricture as an adjuvant treatment to dilatation therapy, as it improved the outcome in the studied cases