Separation and purification of biomacromolecules either in biopharmaceuticals and fine chemicals manufacturing, or in diagnostics and biological characterization, can substantially benefit from application of microfluidic devices. Small volumes of equipment, very efficient mass and heat transfer together with high process control result in process intensification, high throughputs, low energy consumption and reduced waste production as compared to conventional processing. This review highlights microfluidics-based separation and purification of proteins and nucleic acids with the focus on liquid–liquid extractions, particularly with biocompatible aqueous two-phase systems, which represent a cost-effective and green alternative. A variety of...
Aqueous two-phase systems are generated by mixing aqueous solutions of two water-soluble polymers, o...
Temperature-dependent aqueous micellar two-phase systems (AMTPSs) have recently been gaining attenti...
This work demonstrates the development of microfluidic compact discs (CDs) for protein purification ...
Separation and purification of biomacromolecules either in biopharmaceuticals and fine chemicals man...
Abstract Separation and identification of molecules and biomolecules such as nucleic acids, proteins...
Separation of micro- and nano-sized biological particles, such as cells, proteins, and nucleotides, ...
Purification of Deoxyribonucleic acid (DNA) by organic-aqueous liquid extraction, also called phenol...
Economic analysis shows that protein separation and purification are a very important aspect of biom...
Temperature-dependent aqueous micellar two-phase systems (AMTPSs) have recently been gaining attenti...
Purification of nucleic acids from a low quantity of bacterial cells in minute volume is important i...
The actual biotechnology industry demands fast and economic upstream and downstream processes to pur...
Microfluidic chips have paved the way for efficient and economical diagnostics of DNA in the biol...
A technique of handling fluids at the submillimeter scale, microfluidics, plays an important role in...
In the framework of our research work, we are developing a microfluidic system that can be used as a...
The actual biotechnology industry demands fast and economic upstream and downstream processes to pur...
Aqueous two-phase systems are generated by mixing aqueous solutions of two water-soluble polymers, o...
Temperature-dependent aqueous micellar two-phase systems (AMTPSs) have recently been gaining attenti...
This work demonstrates the development of microfluidic compact discs (CDs) for protein purification ...
Separation and purification of biomacromolecules either in biopharmaceuticals and fine chemicals man...
Abstract Separation and identification of molecules and biomolecules such as nucleic acids, proteins...
Separation of micro- and nano-sized biological particles, such as cells, proteins, and nucleotides, ...
Purification of Deoxyribonucleic acid (DNA) by organic-aqueous liquid extraction, also called phenol...
Economic analysis shows that protein separation and purification are a very important aspect of biom...
Temperature-dependent aqueous micellar two-phase systems (AMTPSs) have recently been gaining attenti...
Purification of nucleic acids from a low quantity of bacterial cells in minute volume is important i...
The actual biotechnology industry demands fast and economic upstream and downstream processes to pur...
Microfluidic chips have paved the way for efficient and economical diagnostics of DNA in the biol...
A technique of handling fluids at the submillimeter scale, microfluidics, plays an important role in...
In the framework of our research work, we are developing a microfluidic system that can be used as a...
The actual biotechnology industry demands fast and economic upstream and downstream processes to pur...
Aqueous two-phase systems are generated by mixing aqueous solutions of two water-soluble polymers, o...
Temperature-dependent aqueous micellar two-phase systems (AMTPSs) have recently been gaining attenti...
This work demonstrates the development of microfluidic compact discs (CDs) for protein purification ...