Nuclear Magnetic Resonance Studies.

This thesis is concerned with the application of nuclear magnetic resonance spectroscopy to reaction kineties, sodium resonance and hydrogen-bonding. In Section 1 a historical introduction to N. M. R. is given. Section 2 deals with the theory of N. M. R. , and the classical approach to it, and concludes with the derivation of the Bloch equations. Section 3 discusses the quantum mechanical approach to the theory of N. M. R. The close proximity of the results of the classical and quantum mechanical approaches is shown. Section 4 deals with the introduction of nuclear density matrices to the theory of N. M. R. Section 5 is mainly concerned with the application of the Bloch equations to reaction kinetics. Chemical shift and multiplet type signal collapses are discussed fully. The last part of this section deals with nuclear magnetization transfer. Section 6 discusses the application of the nuclear density matrix to reaction kinetics. Section 7a contains studies on the hydration of acetaldehyde, propionaldehyde and diacetyl. The equilibrium constants of the hydration were obtained. The hydrogen ion catalysis of the hydration of acetaldehyde and propionaldehyde was observed, and a rate law obtained for the former case. An explanation of the observed anomalous behaviour of the acetaldehyde hydration is given. Section 7b contains the study of the hydration of pyruvic acid. The equilibrium constant and the rate law of the hydrogen ion catalysis are discussed. Section 8 contains a study made on sodium Na23 magnetic resonance. The dependance of the intensity and half-width on the concentration of sodium hydroxide and chloride is given in detail. Section 9 contains a study of the hydrogen-bonding of some substituted phenols. The results indicate that in an inert solvent, phenols form mainly cyclic trimers. The equilibrium constants were obtained