Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal melatonin synthesis, and/or a phase-shift of the circadian oscillator. As recent evidence has suggested that extraocular light exposure may cause phase-shifts of the circadian clock, we have investigated whether suppression of melatonin can be induced by the same type of light exposure. In the first study subjects’ eyes were exposed to white light (2250 lux for 30 min) via a fibre optic cable. As expected, suppression of nighttime plasma melatonin levels (61 ± 6%) was observed. In the second study, light of the same quality but higher intensity (14,000 or 67,500 lux for 180 mins) was delivered in the same manner to the popliteal region behind...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...
Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal ...
Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal ...
Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal ...
Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal ...
Light can influence physiology and performance of humans in two distinct ways. It can acutely change...
Preliminary work in humans suggests that extraocular light can shift circadian phase. If confirmed, ...
Light can influence physiology and performance of humans in two distinct ways. It can acutely change...
Light can influence physiology and performance of humans in two distinct ways. It can acutely change...
The eye is a complex organ involved in the input pathway of circadian entrainment. Non-image forming...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...
Abstract The mammalian retina contains both visual and circadian photo-receptors. In humans, nocturn...
Abstract The mammalian retina contains both visual and circadian photo-receptors. In humans, nocturn...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...
Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal ...
Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal ...
Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal ...
Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal ...
Light can influence physiology and performance of humans in two distinct ways. It can acutely change...
Preliminary work in humans suggests that extraocular light can shift circadian phase. If confirmed, ...
Light can influence physiology and performance of humans in two distinct ways. It can acutely change...
Light can influence physiology and performance of humans in two distinct ways. It can acutely change...
The eye is a complex organ involved in the input pathway of circadian entrainment. Non-image forming...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...
Abstract The mammalian retina contains both visual and circadian photo-receptors. In humans, nocturn...
Abstract The mammalian retina contains both visual and circadian photo-receptors. In humans, nocturn...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...
The mammalian retina contains both visual and circadian photoreceptors. In humans, nocturnal stimula...