Sea-level change in the Mediterranean Sea during glacial cycles is determined by the temporally variable eustatic change and by the spatially variable glacio-hydro-isostatic response of the earth and ocean to the growth and decay of ice sheets. Superimposed upon this are the relative changes from any vertical tectonic movement of the land. For sites that are either tectonically stable or where the magnitude of tectonic uplift is known, comparisons of observed change with predictions of the glacio-hydro-eustatic signals provide constraints on the earth–ice parameters used. The resulting predictive models can then be used to interpolate sea-level change and shoreline migration between the spatially and temporally limited observational data se...