The most insidious pandemic of modern life does not arise from an infectious agent but rather from malnutrition. With its global incidence tripling over the past three decades, obesity is a major public health concern. Obesity’s rising prevalence has also illuminated its impact on communicable diseases. Following the 2009 H1N1 influenza A virus pandemic, obesity was identified as a risk factor for increased disease severity and mortality in infected individuals. Obesity causes a chronic state of meta-inflammation with systemic implications for immunity, including delayed antiviral responses to influenza virus infection, poor recovery, and impaired immunological memory. However, the majority of past work neglected the innate responses, espec...
Obese individuals are more susceptible to hospitalization and death from infection with the 2009 pan...
The role of obesity in the pathophysiology of respiratory virus infections has become particularly a...
Acute inflammation is a critical host defense response during viral infection. When dysregulated, in...
With the rising prevalence of obesity has come an increasing awareness of its impact on communicable...
Currently, 50% of the adult population worldwide is overweight or obese. In these studies, we demons...
Background: We live in an ‘obesogenic environment’ in which overconsumption of affordable, energy-de...
Influenza, a highly contagious respiratory tract infection, affects millions of adults and children ...
Inflammation is a double-edged sword – it is needed to fight against infection, yet it results in ti...
Obesity is a well-recognized risk factor for severe influenza infections but the mechanisms underlyi...
Obesity is now a prevalent disease worldwide and has a multi-factorial etiology. Several viruses or ...
In both humans and animal models, obesity leads to a dysregulated immune response; however, the effe...
The incidence of obesity worldwide has reached epidemic proportions. This has had a significant econ...
Previous work from our laboratory demonstrated that obese mice have alterations in antiviral cytokin...
Acknowledgements: M.A. was supported by a Wellcome Trust/Imperial College Clinical Research Training...
From the beginning of 2020, the governments and the health systems around the world are tackling inf...
Obese individuals are more susceptible to hospitalization and death from infection with the 2009 pan...
The role of obesity in the pathophysiology of respiratory virus infections has become particularly a...
Acute inflammation is a critical host defense response during viral infection. When dysregulated, in...
With the rising prevalence of obesity has come an increasing awareness of its impact on communicable...
Currently, 50% of the adult population worldwide is overweight or obese. In these studies, we demons...
Background: We live in an ‘obesogenic environment’ in which overconsumption of affordable, energy-de...
Influenza, a highly contagious respiratory tract infection, affects millions of adults and children ...
Inflammation is a double-edged sword – it is needed to fight against infection, yet it results in ti...
Obesity is a well-recognized risk factor for severe influenza infections but the mechanisms underlyi...
Obesity is now a prevalent disease worldwide and has a multi-factorial etiology. Several viruses or ...
In both humans and animal models, obesity leads to a dysregulated immune response; however, the effe...
The incidence of obesity worldwide has reached epidemic proportions. This has had a significant econ...
Previous work from our laboratory demonstrated that obese mice have alterations in antiviral cytokin...
Acknowledgements: M.A. was supported by a Wellcome Trust/Imperial College Clinical Research Training...
From the beginning of 2020, the governments and the health systems around the world are tackling inf...
Obese individuals are more susceptible to hospitalization and death from infection with the 2009 pan...
The role of obesity in the pathophysiology of respiratory virus infections has become particularly a...
Acute inflammation is a critical host defense response during viral infection. When dysregulated, in...