A Study of Serum Total Calcium and Calcium Phosphorus Ratio in Primary Hypertension and Its Role Predicting the Severity of the Disease

INTRODUCTION: Hypertension significantly increases the risk of mortality and morbidity of cerebrovascular accidents (ischemic and hemorrhagic) coronary artery disease, congestive heart failure, chronic kidney failure, and peripheral vascular diseases. Hypertension related complications have become one of the most important contributor to preventable deaths and diseases in our country too, with an alarmingly increasing rate in the rural areas. More than 140 million people are said to be suffering from hypertension in India. AIMS AND OBJECTIVES: 1.To study the levels of serum calcium and calcium phosphorus ratio in patients with primary hypertension. 2.to correlate serum calcium and calcium /phosphorus ratio with blood pressure. STUDY POPULATION A total of 102 subjects of primary hypertension satisfying inclusion and exclusion criteria visiting medicine OPD in Govt. Kilpauk Medical College and Hospital. SETTINGS AND DESIGN: A cross sectional study involving 102 subjects. Concentrations of serum total calcium and serum calcium phosphorus ratio were measured in the participants. RESULTS: The study showed that serum total calcium were significantly reduced and calcium phosphorus ration were increased which caused the cardiovascular morbidity. CONCLUSIONS: Primary hypertension has an inverse association with serum total calcium and negative correlation with calcium phosphorus ratio which suggests a no role in the pathogenesis of essential hypertension