Introduction Thromboembolism (TE) is a common and serious toxicity of acute lymphoblastic leukemia (ALL) treatment, but studies of genetic predisposition have been underpowered with conflicting results. We tested whether TE in ALL and TE in the general adult population have a shared genetic etiology. Materials and methods We prospectively registered TE events and collected germline DNA in patients 1.0–45.9 years in the Nordic Society of Pediatric Hematology and Oncology (NOPHO) ALL2008 study (7/2008–7/2016). Based on summary statistics from two large genome-wide association studies (GWAS) on venous TE in adults (the International Network of VENous Thromboembolism Clinical Research Networks (INVENT) consortium and the UK Biobank), we perform...
Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...
PubMedID: 21459794Acute lymphoblastic leukemia is the major pediatric cancer in developed countries....
Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...
Introduction Thromboembolism (TE) is a common and serious toxicity of acute lymphoblastic leukemia ...
To access publisher's full text version of this article, please click on the hyperlink in Additional...
Symptomatic venous thromboembolism (VTE) occurs in five percent of children treated for acute lympho...
Symptomatic venous thromboembolism (VTE) occurs in five percent of children treated for acute lympho...
Introduction: Thromboembolism is a serious toxicity of acute lymphoblastic leukemia treatment, and c...
BACKGROUND:Genome-wide association studies (GWAS) of childhood cancers remain limited, highlighting ...
AAcute lymphoblastic leukemia (ALL) in adolescents and young adults (AYA) is characterized by distin...
Symptomatic venous thromboembolism (VTE) occurs in five percent of children treated for acute lympho...
Background: Acute lymphoblastic leukemia (ALL) is a complex disease with genetic background. The gen...
Every year, acute lymphoblastic leukaemia (ALL) affects about 400 children aged <15 years in France,...
Venous thromboembolism (VTE), a collective term for deep vein thrombosis and pulmonary embolism, is ...
Symptomatic venous thromboembolism (VTE) is diagnosed in 3%-14% of patients during pediatric acute l...
Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...
PubMedID: 21459794Acute lymphoblastic leukemia is the major pediatric cancer in developed countries....
Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...
Introduction Thromboembolism (TE) is a common and serious toxicity of acute lymphoblastic leukemia ...
To access publisher's full text version of this article, please click on the hyperlink in Additional...
Symptomatic venous thromboembolism (VTE) occurs in five percent of children treated for acute lympho...
Symptomatic venous thromboembolism (VTE) occurs in five percent of children treated for acute lympho...
Introduction: Thromboembolism is a serious toxicity of acute lymphoblastic leukemia treatment, and c...
BACKGROUND:Genome-wide association studies (GWAS) of childhood cancers remain limited, highlighting ...
AAcute lymphoblastic leukemia (ALL) in adolescents and young adults (AYA) is characterized by distin...
Symptomatic venous thromboembolism (VTE) occurs in five percent of children treated for acute lympho...
Background: Acute lymphoblastic leukemia (ALL) is a complex disease with genetic background. The gen...
Every year, acute lymphoblastic leukaemia (ALL) affects about 400 children aged <15 years in France,...
Venous thromboembolism (VTE), a collective term for deep vein thrombosis and pulmonary embolism, is ...
Symptomatic venous thromboembolism (VTE) is diagnosed in 3%-14% of patients during pediatric acute l...
Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...
PubMedID: 21459794Acute lymphoblastic leukemia is the major pediatric cancer in developed countries....
Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...