A wide range of Internet of Things (IoT) applications require powerful, energy-efficient, and flexible end nodes to acquire data from multiple sources, process and distill the sensed data through near-sensor data analytics algorithms, and transmit it wirelessly. This work presents Arnold : a 0.5-to-0.8-V, 46.83- μW /MHz, 600-MOPS fully programmable RISC-V microcontroller unit (MCU) fabricated in 22-nm Globalfoundries GF22FDX (GF22FDX) technology, coupled with a state-of-the-art (SoA) microcontroller to an embedded field-programmable gate array (eFPGA). We demonstrate the flexibility of the system-on-chip (SoC) to tackle the challenges of many emerging IoT applications, such as interfacing sensors and accelerators with nonstandard interfaces...