Azithromycin (AZI) is used for its antibiotic and antimalarial properties in pregnancy. Reported estimates of AZI breast milk transfer, based on concentrations in mostly single samples from small numbers of women, have suggested that infant intake is safe. To better characterize infant intake and the associated potential benefits and risks, AZI was measured by liquid chromatography-mass spectrometry in four breast milk samples taken over 28 days postpartum from each of 20 Gambian women given 2 g AZI during labor. A population pharmacokinetic model utilizing published parameters for AZI disposition in pregnancy, the present breast milk concentrations, and increasing/decreasing sigmoid maximum-effect (Emax) functions adequately described temp...
BackgroundTreatment with nifurtimox (NF) for Chagas disease is discouraged during breast-feeding bec...
Optimal dosing of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy r...
Tacrolimus, an immunosuppressant drug used orally fororgan transplantation, exhibits variable but us...
ObjectiveTo assess the effect of administering an oral dose of 2g of azithromycin in Gambian women d...
Transfer of piperaquine (PQ) into breast milk was examined in 27 Papua New Guinean women given a 3-d...
ObjectiveTo assess the effect of administering an oral dose of 2g of azithromycin in Gambian women d...
Bacterial sepsis remains a leading cause of death among neonates with Staphylococcus aureus, group B...
Aims: The aim of the present study was to investigate the safety, tolerability and pharmacokinetics ...
Introduction Women with Chagas disease receiving treatment with nifurtimox are discouraged from brea...
BACKGROUND:Remarkable progress has been achieved in the identification of HIV infection in pregnant ...
The study objectives were to refine the population pharmacokinetics (PK) model, determine microbial ...
The health, economic, and sociologic benefits of breastfeeding are substantial. As a result, women a...
Background: Oral azithromycin given to women in labor decreases maternal and neonatal bacterial carr...
AbstractBacterial sepsis remains a leading cause of death among neonates with Staphylococcus aureus,...
Introduction: Maternal and neonatal infections are among the most frequent causes of maternal and ne...
BackgroundTreatment with nifurtimox (NF) for Chagas disease is discouraged during breast-feeding bec...
Optimal dosing of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy r...
Tacrolimus, an immunosuppressant drug used orally fororgan transplantation, exhibits variable but us...
ObjectiveTo assess the effect of administering an oral dose of 2g of azithromycin in Gambian women d...
Transfer of piperaquine (PQ) into breast milk was examined in 27 Papua New Guinean women given a 3-d...
ObjectiveTo assess the effect of administering an oral dose of 2g of azithromycin in Gambian women d...
Bacterial sepsis remains a leading cause of death among neonates with Staphylococcus aureus, group B...
Aims: The aim of the present study was to investigate the safety, tolerability and pharmacokinetics ...
Introduction Women with Chagas disease receiving treatment with nifurtimox are discouraged from brea...
BACKGROUND:Remarkable progress has been achieved in the identification of HIV infection in pregnant ...
The study objectives were to refine the population pharmacokinetics (PK) model, determine microbial ...
The health, economic, and sociologic benefits of breastfeeding are substantial. As a result, women a...
Background: Oral azithromycin given to women in labor decreases maternal and neonatal bacterial carr...
AbstractBacterial sepsis remains a leading cause of death among neonates with Staphylococcus aureus,...
Introduction: Maternal and neonatal infections are among the most frequent causes of maternal and ne...
BackgroundTreatment with nifurtimox (NF) for Chagas disease is discouraged during breast-feeding bec...
Optimal dosing of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy r...
Tacrolimus, an immunosuppressant drug used orally fororgan transplantation, exhibits variable but us...