A new and efficient synthesis of pyridine-based heteroaromatic boronic acid derivatives is reported through a novel diboration/6π-electrocyclization strategy. This method delivers a range of functionalized heterocycles from readily available starting materials
Heterocycles are prevalent within biologically active molecules, with >70% of FDA approved drugs fea...
Alkynylboranes show unprecedented reactivity in their [4 + 2] cycloaddition of sydnones offering acc...
Conventional methods carrying out C(sp2)−C(sp2) bond formations are typically mediated by transition...
A new and efficient synthesis of pyridine‐based heteroaromatic boronic acid derivatives is reported ...
A new and efficient synthesis of pyridine-based heteroaromatic boronic acid derivatives is reported ...
E-oxime ethers are found to be significantly more reactive in electrocyclizations than their Z-count...
We demonstrate that a diboration‐electrocyclization sequence provides access to a range of pyridine ...
The greater geometric lability of hydrazones compared to that of oxime ethers is used as a basis to ...
This thesis was previously under moratorium in Chemistry department (GSK) from 26/10/17 until 3 Sept...
A convenient one-pot C-H alkenylation/electrocyclization/aromatization sequence has been developed f...
The aza-Diels–Alder cycloaddition of 1,2,4-triazines with alkynes offers a rapid and convenient meth...
A metal-free protocol for the synthesis of substituted 1,6-dihydropyridines with quaternary stereoge...
Carbene-stabilized diborynes of the form LBBL (L = NHC or CAAC) induce rapid, high yielding, intermo...
A novel Suzuki-Miyaura protocol is described that enables the exhaustive alkylation of polychlorinat...
The combination of 1-benzyl-1,4-dihydropyridines with the strong Lewis acid, B(C6F5)3, generates a s...
Heterocycles are prevalent within biologically active molecules, with >70% of FDA approved drugs fea...
Alkynylboranes show unprecedented reactivity in their [4 + 2] cycloaddition of sydnones offering acc...
Conventional methods carrying out C(sp2)−C(sp2) bond formations are typically mediated by transition...
A new and efficient synthesis of pyridine‐based heteroaromatic boronic acid derivatives is reported ...
A new and efficient synthesis of pyridine-based heteroaromatic boronic acid derivatives is reported ...
E-oxime ethers are found to be significantly more reactive in electrocyclizations than their Z-count...
We demonstrate that a diboration‐electrocyclization sequence provides access to a range of pyridine ...
The greater geometric lability of hydrazones compared to that of oxime ethers is used as a basis to ...
This thesis was previously under moratorium in Chemistry department (GSK) from 26/10/17 until 3 Sept...
A convenient one-pot C-H alkenylation/electrocyclization/aromatization sequence has been developed f...
The aza-Diels–Alder cycloaddition of 1,2,4-triazines with alkynes offers a rapid and convenient meth...
A metal-free protocol for the synthesis of substituted 1,6-dihydropyridines with quaternary stereoge...
Carbene-stabilized diborynes of the form LBBL (L = NHC or CAAC) induce rapid, high yielding, intermo...
A novel Suzuki-Miyaura protocol is described that enables the exhaustive alkylation of polychlorinat...
The combination of 1-benzyl-1,4-dihydropyridines with the strong Lewis acid, B(C6F5)3, generates a s...
Heterocycles are prevalent within biologically active molecules, with >70% of FDA approved drugs fea...
Alkynylboranes show unprecedented reactivity in their [4 + 2] cycloaddition of sydnones offering acc...
Conventional methods carrying out C(sp2)−C(sp2) bond formations are typically mediated by transition...
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