A general and long-standing belief in the proof complexity community asserts that there is a close connection between progress in lower bounds for Boolean circuits and progress in proof size lower bounds for strong propositional proof systems. Although there are famous examples where a transfer from ideas and techniques from circuit complexity to proof complexity has been effective, a formal connection between the two areas has never been established so far. Here we provide such a formal relation between lower bounds for circuit classes and lower bounds for Frege systems for quantified Boolean formulas (QBF). Starting from a propositional proof system P we exhibit a general method how to obtain a QBF proof system P+∀red{P}, which is inspire...