Obesity is a major health burden with an increased risk of cardiovascular morbidity and mortality. Endothelial dysfunction is pivotal to the development of cardiovascular disease (CVD). In relation to this, adipose tissue secreted factors termed "adipokines" have been reported to modulate endothelial dysfunction. In this review, we focus on two of the most abundant circulating adipokines, that is, leptin and adiponectin, in the development of endothelial dysfunction. Leptin has been documented to influence a multitude of organ systems, that is, central nervous system (appetite regulation, satiety factor) and cardiovascular system (endothelial dysfunction leading to atherosclerosis). Adiponectin, circulating at a much higher concentration, e...
Adipose tissue is a critical regulator of vascular function, which until recently had been virtually...
For many decades, adipose tissue was considered as an inactive body compartment that was only used a...
Obesity and obesity related diseases are a major public health problem. Recent studies have shown th...
Obesity is a major health burden with an increased risk of cardiovascular morbidity and mortality. E...
Copyright © 2015 Raghu Adya et al. This is an open access article distributed under the Creative Com...
Increasing adipose tissue mass in obesity directly correlates with elevated circulating leptin level...
Obesity, the most common nutritional disorder in industrial countries, is associated with increased ...
Adipocytes are nowadays recognised as cells able to produce and secrete a large variety of active su...
The discovery of leptin in 1994 sparked dramatic new interest in the study of white adipose tissue. ...
Obesity, which is a worldwide epidemic, confers increased risk for multiple serious conditions incl...
Obesity is characterized by pathological adipose tissue (AT) expansion. While healthy AT expansion e...
The heart and blood vessels are surrounded by epicardial and perivascular adipose tissues, respectiv...
Obesity is characterized by the excessive deposition of fat that may interfere with the normal metab...
Adiponectin and leptin are two abundant adipokines with different properties but both described such...
Adiponectin and leptin are two abundant adipokines with different properties but both described such...
Adipose tissue is a critical regulator of vascular function, which until recently had been virtually...
For many decades, adipose tissue was considered as an inactive body compartment that was only used a...
Obesity and obesity related diseases are a major public health problem. Recent studies have shown th...
Obesity is a major health burden with an increased risk of cardiovascular morbidity and mortality. E...
Copyright © 2015 Raghu Adya et al. This is an open access article distributed under the Creative Com...
Increasing adipose tissue mass in obesity directly correlates with elevated circulating leptin level...
Obesity, the most common nutritional disorder in industrial countries, is associated with increased ...
Adipocytes are nowadays recognised as cells able to produce and secrete a large variety of active su...
The discovery of leptin in 1994 sparked dramatic new interest in the study of white adipose tissue. ...
Obesity, which is a worldwide epidemic, confers increased risk for multiple serious conditions incl...
Obesity is characterized by pathological adipose tissue (AT) expansion. While healthy AT expansion e...
The heart and blood vessels are surrounded by epicardial and perivascular adipose tissues, respectiv...
Obesity is characterized by the excessive deposition of fat that may interfere with the normal metab...
Adiponectin and leptin are two abundant adipokines with different properties but both described such...
Adiponectin and leptin are two abundant adipokines with different properties but both described such...
Adipose tissue is a critical regulator of vascular function, which until recently had been virtually...
For many decades, adipose tissue was considered as an inactive body compartment that was only used a...
Obesity and obesity related diseases are a major public health problem. Recent studies have shown th...