Phage Antibiotic Antagonism of Escherichia coli B and T4 Phage

Antibiotic resistance has resulted in researchers finding new methods for treating diseases caused by pathogenic bacteria. Antibiotic resistance forms due to the presence of plasmids and mutations in the bacterial genome. Phage Antibiotic synergy has been reported when exposing bacteria to phages in previous studies. Bacterial immune mechanisms, specifically those that aid against bacteriophages, have been exploited by researchers as a potential treatment for infection and diseases. These mechanism includes Superinfection (Sie), Abortive infection, surface modification, etc. Escherichia coli B is a bacteria that contains an outer membrane with receptors, porins, lipopolysaccharides, and other surface molecules that aid in defense and metabolism. Escherichia coli B is also a motile bacteria, (flagella) a mesophile, and facultative anaerobe