New precompetitive ways of working in the pharmaceutical industry are driving the development of new informatics systems to enable their execution and management. The European Lead Factory (ELF) is a precompetitive, 30-partner collaboration between academic groups, small-medium enterprises and pharmaceutical companies created to discover small molecule hits against novel biological targets. A unique HTS screening and triage workflow has been developed to balance the intellectual property and scientific requirements of all the partners. Here, we describe the ELF Honest Data Broker, a cloud-based informatics system providing the scientific triage tools, fine-grained permissions and management tools required to implement the workflow.</p
Open data is considered the new oil. As oil can be used to produce fertilisers, pesticides, lubrican...
The development of chemical tool compounds becomes increasingly important for chemical biology resea...
Through the European Lead Factory model, industry-standard high-throughput screening and hit validat...
New precompetitive ways of working in the pharmaceutical industry are driving the development of new...
New precompetitive ways of working in the pharmaceutical industry are driving the development of new...
The European Lead Factory (ELF) provides preclinical researchers in Europe with an integrated hit id...
The European Lead Factory (ELF) is a unique collaborative public–private partnership aiming to deliv...
The European Lead Factory (ELF) is a pan-European public-private partnership established in 2013 and...
The European Lead Factory (ELF) is a public-private consortium aimed at delivering high quality hit ...
The Joint European Compound Library (JECL) is a new high-throughput screening collection aimed at dr...
High-throughput screening (HTS) represents a major cornerstone of drug discovery. The availability o...
High-throughput screening (HTS) represents a major cornerstone of drug discovery. The availability o...
The identification of high-quality starting points for drug discovery is an enduring challenge in me...
The Joint European Compound Library (JECL) is a new high-throughput screening collection aimed at dr...
With industry increasingly sourcing preclinical drug discovery projects from academia it is importan...
Open data is considered the new oil. As oil can be used to produce fertilisers, pesticides, lubrican...
The development of chemical tool compounds becomes increasingly important for chemical biology resea...
Through the European Lead Factory model, industry-standard high-throughput screening and hit validat...
New precompetitive ways of working in the pharmaceutical industry are driving the development of new...
New precompetitive ways of working in the pharmaceutical industry are driving the development of new...
The European Lead Factory (ELF) provides preclinical researchers in Europe with an integrated hit id...
The European Lead Factory (ELF) is a unique collaborative public–private partnership aiming to deliv...
The European Lead Factory (ELF) is a pan-European public-private partnership established in 2013 and...
The European Lead Factory (ELF) is a public-private consortium aimed at delivering high quality hit ...
The Joint European Compound Library (JECL) is a new high-throughput screening collection aimed at dr...
High-throughput screening (HTS) represents a major cornerstone of drug discovery. The availability o...
High-throughput screening (HTS) represents a major cornerstone of drug discovery. The availability o...
The identification of high-quality starting points for drug discovery is an enduring challenge in me...
The Joint European Compound Library (JECL) is a new high-throughput screening collection aimed at dr...
With industry increasingly sourcing preclinical drug discovery projects from academia it is importan...
Open data is considered the new oil. As oil can be used to produce fertilisers, pesticides, lubrican...
The development of chemical tool compounds becomes increasingly important for chemical biology resea...
Through the European Lead Factory model, industry-standard high-throughput screening and hit validat...