Many-core on the Grid: from exploration to production

High Energy Physics experiments have successfully demonstrated that many-core devices such as GPUs can be used to accelerate critical algorithms in their software. There is now increasing community interest for many-core devices to be made available on the LHC Computing Grid infrastructure. Despite anticipated usage there is no standard method available to run many-core applications in distributed computing environments and before many-core resources are made available on the Grid a number of operational issues such as job scheduling and resource discovery will need to be addressed. The key challenges for Grid-enabling many-core devices will be discussed