Hypertension is a major cardiovascular risk factor. Of the many processes involved in the pathophysiology of hypertension, vascular damage due to oxidative stress (excess bioavailability of reactive oxygen species [ROS]) is particularly important. Physiologically, ROS regulate vascular function through redox-sensitive signalling pathways. In hypertension, oxidative stress promotes endothelial dysfunction, vascular remodelling, and inflammation, leading to vascular damage. Vascular ROS are derived primarily by nicotinamide adenine dinucleotide phosphate oxidases, which are prime targets for therapeutic development. Although experimental evidence indicates a causative role for oxidative stress in hypertension, human data are less convincing. ...
Oxidative stress, a state of excessive reactive oxidative species activity, is associated with vascu...
The cellular metabolism of oxygen generates potentially deleterious reactive oxygen species, includi...
As a major cause of morbidity and mortality globally, hypertension remains a serious threat to globa...
Hypertension is a major cardiovascular risk factor. Of the many processes involved in the pathophysi...
Hypertension is a major cardiovascular risk factor. Of the many processes involved in the pathophysi...
Reactive oxygen species (ROS) act as signaling molecules that control physiological processes, inclu...
Increased vascular production of reactive oxygen species (ROS; termed oxidative stress) has been imp...
Metabolism of oxygen by cells generates potentially deleterious reactive oxygen species (ROS). Under...
Reactive oxygen species (ROS) influence many physiological processes including host defense, hormone...
Hypertension is a major contributor to the development of renal failure, cardiovascular disease, and...
Reactive oxygen species (ROS) are signaling molecules that influence many physiological processes. I...
Many factors have been implicated in the pathophysiology of hypertension such as upregulation of the...
The etiology of hypertension involves complex interactions among genetic, environmental, and pathoph...
Abstract—Metabolism of oxygen by cells generates potentially deleterious reactive oxygen species (RO...
Reactive oxygen species (ROS), including superoxide (*O2-), hydrogen peroxide (H2O2), and hydroxyl a...
Oxidative stress, a state of excessive reactive oxidative species activity, is associated with vascu...
The cellular metabolism of oxygen generates potentially deleterious reactive oxygen species, includi...
As a major cause of morbidity and mortality globally, hypertension remains a serious threat to globa...
Hypertension is a major cardiovascular risk factor. Of the many processes involved in the pathophysi...
Hypertension is a major cardiovascular risk factor. Of the many processes involved in the pathophysi...
Reactive oxygen species (ROS) act as signaling molecules that control physiological processes, inclu...
Increased vascular production of reactive oxygen species (ROS; termed oxidative stress) has been imp...
Metabolism of oxygen by cells generates potentially deleterious reactive oxygen species (ROS). Under...
Reactive oxygen species (ROS) influence many physiological processes including host defense, hormone...
Hypertension is a major contributor to the development of renal failure, cardiovascular disease, and...
Reactive oxygen species (ROS) are signaling molecules that influence many physiological processes. I...
Many factors have been implicated in the pathophysiology of hypertension such as upregulation of the...
The etiology of hypertension involves complex interactions among genetic, environmental, and pathoph...
Abstract—Metabolism of oxygen by cells generates potentially deleterious reactive oxygen species (RO...
Reactive oxygen species (ROS), including superoxide (*O2-), hydrogen peroxide (H2O2), and hydroxyl a...
Oxidative stress, a state of excessive reactive oxidative species activity, is associated with vascu...
The cellular metabolism of oxygen generates potentially deleterious reactive oxygen species, includi...
As a major cause of morbidity and mortality globally, hypertension remains a serious threat to globa...