Process Evaluation of Complex Interventions Guidance: UK Medical Research Council (MRC) Guidance

Updated MRC guidance for evaluation of complex interventions published in 2008 (Craig et al.2008) highlighted the value of process evaluation within trials of complex interventions in order to understand implementation, the mechanisms through which interventions produce change, and the role of context in shaping implementation and effectiveness. However, it provided limited insight into how to conduct a good quality process evaluation.<p></p> New MRC guidance for process evaluation of complex interventions has been produced on behalf of the MRC Population Health Sciences Research Network by a group of 11 health researchers from 8 universities, in consultation with a wider stakeholder group. The author group was chaired by Dr Janis Baird, MRC Lifecourse Epidemiology Unit, University of Southampton. The development of the guidance was led by Dr Graham Moore, DECIPHer, Cardiff University.<p></p> The document begins with an introductory chapter which sets out the reasons why we need process evaluation, before presenting a new framework which expands on the aims for process evaluation identified within the 2008 complex interventions guidance (implementation, mechanisms of impact and context). It then presents discrete sections on process evaluation theory (Section A) and process evaluation practice (Section B), before offering a number of detailed case studies from process evaluations conducted by the authors (Section C).<p></p&gt