- Introduction: The aim of this study was to examine the prevalence and functional effects of antibodies directed against Factor (F)Xa and other serine proteases (SP) in patients with antiphospholipid syndrome (APS). - Methods: Serum from patients with APS (n = 59), systemic lupus erythematosus (SLE; n = 106), other autoimmune rheumatic disease (ARD; n = 63) and 40 healthy controls (HC) were tested for IgG activity against thrombin (Thr), FXa, FVIIa, phosphatidylserine (PS)/FXa and antithrombin (AT)-III by enzyme-linked immunosorbent assay (ELISA). Anti-FXa positive IgG were purified to measure their avidity by chaotropic ELISA and functional effects upon clotting time (FXa-ACT) and FXa enzymatic activity (± AT-III). - Results: Anti-FXa I...
Background: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
Background: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
Introduction The aim of this study was to examine the prevalence and functional effects of antibodie...
The aim of this study was to examine the prevalence and functional effects of antibodies directed ag...
Factor (F) Xa reactive IgG isolated from patients with antiphospholipid syndrome (APS) display highe...
OBJECTIVES: The significance of antibodies directed against activated factor X (FXa) and thrombin (T...
Antiphospholipid Ab have been shown to promote thrombosis and fetal loss in the antiphospholipid syn...
We previously reported that some human antiphospholipid Abs( aPL) in patients with the anti phosphol...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
Background: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
Background: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
Introduction The aim of this study was to examine the prevalence and functional effects of antibodie...
The aim of this study was to examine the prevalence and functional effects of antibodies directed ag...
Factor (F) Xa reactive IgG isolated from patients with antiphospholipid syndrome (APS) display highe...
OBJECTIVES: The significance of antibodies directed against activated factor X (FXa) and thrombin (T...
Antiphospholipid Ab have been shown to promote thrombosis and fetal loss in the antiphospholipid syn...
We previously reported that some human antiphospholipid Abs( aPL) in patients with the anti phosphol...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
Background: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
Background: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...
BACKGROUND: Arterial and venous thrombosis are both common in antiphospholipid syndrome (APS). Recen...