In many areas of science, models are used to describe attributes of complex systems. These models are generally themselves highly complex functions of their inputs, and can be computationally expensive to evaluate. Often, these models have parameters which must be estimated using data from the real system. In this paper, we address the problem of using prior information supplied by the model, in conjunction with prior beliefs about its parameters, to design the collection of data such that it is optimal for decisions which must be made using posterior beliefs about the model parameters. Optimal design calculations do not generally have a closed form solution, so we propose a Bayes linear analysis to find an approximately optimal design. We ...
Scientists perform experiments to collect evidence supporting one or another hypothesis or theory. E...
Motivation: Systems biology employs mathematical modelling to further our understanding of biochemic...
This thesis progresses Bayesian experimental design by developing novel methodologies and extensions...
In many areas of science, models are used to describe attributes of complex systems. These models ar...
Bayesian experimental design is a fast growing area of research with many real-world applications. A...
The emphasis in this work is on derivation of optimal Bayes inferences and designs in relatively une...
The design of an experiment can be always be considered at least implicitly Bayesian, with prior kno...
In a statistical or physical model, it is often the case that a set of design inputs must be selecte...
In a statistical or physical model, it is often the case that a set of design inputs must be selecte...
Thesis: S.M., Massachusetts Institute of Technology, Computation for Design and Optimization Program...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Aeronautics and Astronautics, 2...
The optimal selection of experimental conditions is essential to maximizing the value of data for in...
In this paper, we argue that some of the prior parameter distributions used in the literature for th...
The use of Bayesian methodologies for solving optimal experimental design problems has increased. Ma...
Optimal experimental design (OED) is the general formalism of sensor placement and decisions about t...
Scientists perform experiments to collect evidence supporting one or another hypothesis or theory. E...
Motivation: Systems biology employs mathematical modelling to further our understanding of biochemic...
This thesis progresses Bayesian experimental design by developing novel methodologies and extensions...
In many areas of science, models are used to describe attributes of complex systems. These models ar...
Bayesian experimental design is a fast growing area of research with many real-world applications. A...
The emphasis in this work is on derivation of optimal Bayes inferences and designs in relatively une...
The design of an experiment can be always be considered at least implicitly Bayesian, with prior kno...
In a statistical or physical model, it is often the case that a set of design inputs must be selecte...
In a statistical or physical model, it is often the case that a set of design inputs must be selecte...
Thesis: S.M., Massachusetts Institute of Technology, Computation for Design and Optimization Program...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Aeronautics and Astronautics, 2...
The optimal selection of experimental conditions is essential to maximizing the value of data for in...
In this paper, we argue that some of the prior parameter distributions used in the literature for th...
The use of Bayesian methodologies for solving optimal experimental design problems has increased. Ma...
Optimal experimental design (OED) is the general formalism of sensor placement and decisions about t...
Scientists perform experiments to collect evidence supporting one or another hypothesis or theory. E...
Motivation: Systems biology employs mathematical modelling to further our understanding of biochemic...
This thesis progresses Bayesian experimental design by developing novel methodologies and extensions...