Individuals born with low renal reserves are predisposed to progressive renal disease and primary hypertension as adults. Experimental evidence for vitamin A (retinol) control of nephrogenesis have led some to propose that maternal vitamin A status during pregnancy is responsible for most of the inborn variation in nephron number in the general population. The extent of collecting duct (CD) arborization during development is a primary determinant of nephron endowment. In the present study, the hypothesis of direct retinoic acid (RA) effects on CD branching morphogenesis was tested using murine inner medullary collecting duct (mIMCD-3) cells. Data presented show that mIMCD-3 cells express retinoic acid receptors (RARs) which mediate...
Retinoids in nephrology: Promises and pitfalls.BackgroundRetinoids, a family of vitamin A metabolite...
Retinoic acid (RA)-signaling is involved in a broad spectrum of cellular processes, including format...
International audienceProliferation of glomerular epithelial cells, including the podocytes, is a ke...
retinoic acid (tRA), which binds retinoic acid receptors (RARs) to modulate gene expression. We and...
Vitamin A is necessary for kidney development and has also been linked to regulation of solute and w...
Retinoic acid is the bioactive derivative of vitamin A, which plays an indispensible role in kidney ...
Metanephros organogenesis is highly stimulated by vitamin A derivatives in organ culture. Vitamin A ...
Regulation of human renal adenocarcinoma cell growth by retinoic acid and its interactions with epid...
Retinoic acid (RA) activates RA receptors (RAR), resulting in RA response element (RARE)-dependent g...
Background: Retinoic acid is the bioactive derivative of vitamin A, which plays an indispensible rol...
<p>A and B: sections of wild type kidneys showing normal distribution of the nephrons. NZ- nephrogen...
Retinoic acid affects the cell cycle and increases total protein content in epithelial cells. Retino...
Cytokine-driven proliferation and inflammation play important roles in the response of the kidney to...
Renal lineages including kidney are derived from intermediate mesoderm, which are differentiated fro...
Kidney tubulogenesis is the initial step in renal organogenesis. The precise molecular determinants ...
Retinoids in nephrology: Promises and pitfalls.BackgroundRetinoids, a family of vitamin A metabolite...
Retinoic acid (RA)-signaling is involved in a broad spectrum of cellular processes, including format...
International audienceProliferation of glomerular epithelial cells, including the podocytes, is a ke...
retinoic acid (tRA), which binds retinoic acid receptors (RARs) to modulate gene expression. We and...
Vitamin A is necessary for kidney development and has also been linked to regulation of solute and w...
Retinoic acid is the bioactive derivative of vitamin A, which plays an indispensible role in kidney ...
Metanephros organogenesis is highly stimulated by vitamin A derivatives in organ culture. Vitamin A ...
Regulation of human renal adenocarcinoma cell growth by retinoic acid and its interactions with epid...
Retinoic acid (RA) activates RA receptors (RAR), resulting in RA response element (RARE)-dependent g...
Background: Retinoic acid is the bioactive derivative of vitamin A, which plays an indispensible rol...
<p>A and B: sections of wild type kidneys showing normal distribution of the nephrons. NZ- nephrogen...
Retinoic acid affects the cell cycle and increases total protein content in epithelial cells. Retino...
Cytokine-driven proliferation and inflammation play important roles in the response of the kidney to...
Renal lineages including kidney are derived from intermediate mesoderm, which are differentiated fro...
Kidney tubulogenesis is the initial step in renal organogenesis. The precise molecular determinants ...
Retinoids in nephrology: Promises and pitfalls.BackgroundRetinoids, a family of vitamin A metabolite...
Retinoic acid (RA)-signaling is involved in a broad spectrum of cellular processes, including format...
International audienceProliferation of glomerular epithelial cells, including the podocytes, is a ke...