The application of precisely timed, short exposures of embryos to specific metabolic inbibitors is a useful method for analysing the biochemical aspects of development. The teratologic approach to the study of the biochemical requirerments of various organogenetic processes in the developing embryo was first formulated by Warkany (1944) who showed that the offspring of female rats maintained on a vitamin A deficient diet had characteristic patterns of malformations. [...
Using the rodent embryo culture techniques of New (1978), it can be demonstrated that, over the 48-h...
The requirement for vitamin A in reproduction was first recognized in the early 1900’s, and its impo...
Three areas of reproductive toxicology have been investigated in this thesis: the development of in ...
Although the fact that man might produce malformed offspring in animals by altering the maternal env...
Exposure of the embryo to environmental chemicals can result in congenital malformations or abortion...
The investigation objects are the blood, blood plasma, homogenate, cytosol, microsomic fraction of t...
Certain short-chain carboxylic acids (SCCA) appear to share a common teratogenic potential, although...
Teratology is the study of birth defects – structural or functional abnormalities that are present a...
Primitive streak stage rat embryos were cultured in serum containing added vitamin A alcohol at conc...
The effects on mucopolysaccharide synthesis in isolated embryonic rat hearts of in vivo and/or in vi...
The potential role of embryonic cells in the IN VITRO bioactivation of teratogens was investigated, ...
Alterations in multiple molecular forms of enzymes have been described during normal embryogenesis. ...
Teratology is the science that studies the causes, mechanisms, and patterns of abnormal development....
Much progress has been made over the past decades in the development of in vitro techniques for the ...
Biomarkers of effect are measurable biochemical, physiological or other alterations within an organi...
Using the rodent embryo culture techniques of New (1978), it can be demonstrated that, over the 48-h...
The requirement for vitamin A in reproduction was first recognized in the early 1900’s, and its impo...
Three areas of reproductive toxicology have been investigated in this thesis: the development of in ...
Although the fact that man might produce malformed offspring in animals by altering the maternal env...
Exposure of the embryo to environmental chemicals can result in congenital malformations or abortion...
The investigation objects are the blood, blood plasma, homogenate, cytosol, microsomic fraction of t...
Certain short-chain carboxylic acids (SCCA) appear to share a common teratogenic potential, although...
Teratology is the study of birth defects – structural or functional abnormalities that are present a...
Primitive streak stage rat embryos were cultured in serum containing added vitamin A alcohol at conc...
The effects on mucopolysaccharide synthesis in isolated embryonic rat hearts of in vivo and/or in vi...
The potential role of embryonic cells in the IN VITRO bioactivation of teratogens was investigated, ...
Alterations in multiple molecular forms of enzymes have been described during normal embryogenesis. ...
Teratology is the science that studies the causes, mechanisms, and patterns of abnormal development....
Much progress has been made over the past decades in the development of in vitro techniques for the ...
Biomarkers of effect are measurable biochemical, physiological or other alterations within an organi...
Using the rodent embryo culture techniques of New (1978), it can be demonstrated that, over the 48-h...
The requirement for vitamin A in reproduction was first recognized in the early 1900’s, and its impo...
Three areas of reproductive toxicology have been investigated in this thesis: the development of in ...