A strain of Penicillium cyaneo-fulvum, isolated in the Department of Bacteriology and Immunology, McGill University by Dr. G. D. Denton in 1947, * was found to produce a toxin neutralizing substance, Noxiversin (Diena, 1954, 1956; Tanner, 1956, 1957; Murray et al., 1958), as well as a separate and distinct antiviral substance (Cooke, 1958, 1960; Cooke and Stevenson, 1965 a, b). The antiviral agent, in both its crude and partially purified forms, was found to reduce the infectivity of influenza virus in embryonated eggs, modified Maitland cultures, monkey kidney cell cultures, and mice (Diena, 1956; Cooke, 1958, 1960; Syeklocha, 1962, 1964; Cooke and Stevenson, 1965b; David-West, 1966)
In 1940 one of us (White) reported that a strain of Aspergillusflavus, grown on certain liquid media...
The results of studies of a newly isolated Serratia species K-57 strain are presented. The strain is...
Natural products provide a vast array of chemical structures to explore in the discovery of new medi...
Penicillium cyaneo-fulvum, which was found growing as a contaminant on a Lowenstein slope in the Cli...
In 1947 a mould was found growing as a contaminant on a Lowenstein's slope which had been inoculated...
Interest in the study of antiviral substances stems from the fact that classical chemotherapy as it ...
In 1947 D.G. Denton (Murray, Denton, Stevenson, and Diena, 1957) isolated a mold, later identified a...
[...] The purpose of the present investigation has been to continue the study of the antiviral subst...
Since the discovery of penicillin by Fleming (1) in 1929 a number of investiga-tions have been carri...
In the early 1890’s Metchnikoff demonstrated that Bacillus subtilis was able to produce substances w...
The formation of more than one antibiotic substance by a single antagonistic organism has been defin...
The initial stimulus to the search for microorganisms which produce therapeutically effective antiba...
With the advent of penicillin many workers sought similar agents that were bacteriostatic or bacteri...
Abstract Microbial natural products possess a wide range of biological and biochemical potential. Am...
Commercially available antiviral drugs, when used in the treatment of viral infections, do not alway...
In 1940 one of us (White) reported that a strain of Aspergillusflavus, grown on certain liquid media...
The results of studies of a newly isolated Serratia species K-57 strain are presented. The strain is...
Natural products provide a vast array of chemical structures to explore in the discovery of new medi...
Penicillium cyaneo-fulvum, which was found growing as a contaminant on a Lowenstein slope in the Cli...
In 1947 a mould was found growing as a contaminant on a Lowenstein's slope which had been inoculated...
Interest in the study of antiviral substances stems from the fact that classical chemotherapy as it ...
In 1947 D.G. Denton (Murray, Denton, Stevenson, and Diena, 1957) isolated a mold, later identified a...
[...] The purpose of the present investigation has been to continue the study of the antiviral subst...
Since the discovery of penicillin by Fleming (1) in 1929 a number of investiga-tions have been carri...
In the early 1890’s Metchnikoff demonstrated that Bacillus subtilis was able to produce substances w...
The formation of more than one antibiotic substance by a single antagonistic organism has been defin...
The initial stimulus to the search for microorganisms which produce therapeutically effective antiba...
With the advent of penicillin many workers sought similar agents that were bacteriostatic or bacteri...
Abstract Microbial natural products possess a wide range of biological and biochemical potential. Am...
Commercially available antiviral drugs, when used in the treatment of viral infections, do not alway...
In 1940 one of us (White) reported that a strain of Aspergillusflavus, grown on certain liquid media...
The results of studies of a newly isolated Serratia species K-57 strain are presented. The strain is...
Natural products provide a vast array of chemical structures to explore in the discovery of new medi...