The biochemist has been aided greatly in recent years in developing his knowledge of the metabolism of organic and inorganic substances in biological systems through the use of isotopes as tracers. Since the chemical properties of an element are determined solely by the number and distribution of electrons surrounding the nucleus, it is apparent that all isotopes of a given element should behave in an identical manner when participating in a chemical reaction. It is this fact which enables one to use separated isotopes to label a compound and to use it as a tracer in a chemical reaction or biological process.[...
In the last decade, there has been a resurgence of interest in the use of stable isotopes of carbon,...
Isotope labeling techniques have become a most valu-able tool in metabolomics and fluxomics [1]. In ...
Gas chromatography-isotope ratio mass spectrometry (GC-IRMS) has made it possible to analyze natural...
Over a century ago, Frederick Soddy provided the first evidence for the existence of isotopes; eleme...
WHEN the chemist approaches the study of a biological system, his first enquiry is usually at the an...
AbstractAs Medicinal Chemists are responsible for the synthesis and optimization of compounds, they ...
In recent years, isotopes have become one of the most potent tools available to the organic chemist ...
At the beginning of 1910s experiments conducted by F.Soddy gave the first demonstration that most of...
The importance of preparing hormonal steroids containing an isotopic carbon atom has been well recog...
Acyl, phosphoryl, and sulfuryl transfer reactions involving esters and amides are ubiquitous in the ...
More than 375 radioactive isotopes of the common chemical elements have been produced by nuclear bom...
The use of isotope labels has had a fundamentally important role in the determination of mechanisms ...
International audienceThe natural isotope abundance in bulk organic matter or tissues is not a suffi...
During the past 15 years there has been a rapid and extensive development of the use of isotopes in ...
The utilization of isotopic labeling is still growing in its use among chemists; the use of hydrogen...
In the last decade, there has been a resurgence of interest in the use of stable isotopes of carbon,...
Isotope labeling techniques have become a most valu-able tool in metabolomics and fluxomics [1]. In ...
Gas chromatography-isotope ratio mass spectrometry (GC-IRMS) has made it possible to analyze natural...
Over a century ago, Frederick Soddy provided the first evidence for the existence of isotopes; eleme...
WHEN the chemist approaches the study of a biological system, his first enquiry is usually at the an...
AbstractAs Medicinal Chemists are responsible for the synthesis and optimization of compounds, they ...
In recent years, isotopes have become one of the most potent tools available to the organic chemist ...
At the beginning of 1910s experiments conducted by F.Soddy gave the first demonstration that most of...
The importance of preparing hormonal steroids containing an isotopic carbon atom has been well recog...
Acyl, phosphoryl, and sulfuryl transfer reactions involving esters and amides are ubiquitous in the ...
More than 375 radioactive isotopes of the common chemical elements have been produced by nuclear bom...
The use of isotope labels has had a fundamentally important role in the determination of mechanisms ...
International audienceThe natural isotope abundance in bulk organic matter or tissues is not a suffi...
During the past 15 years there has been a rapid and extensive development of the use of isotopes in ...
The utilization of isotopic labeling is still growing in its use among chemists; the use of hydrogen...
In the last decade, there has been a resurgence of interest in the use of stable isotopes of carbon,...
Isotope labeling techniques have become a most valu-able tool in metabolomics and fluxomics [1]. In ...
Gas chromatography-isotope ratio mass spectrometry (GC-IRMS) has made it possible to analyze natural...