Effects of sodium and calcium ions on the release of acetylcholine at frog and rat myoneural junctions.

From the 1790 's, when Galvani and Volta (R. M. Green, 1953) experimented with animal electricity, until the beginning of the 20th century, there was little reason to doubt that excitation passed from nerve to muscle electrically (Kuhne, 1888). Protoplasmic continuity was assumed, despite increasing evidence to the contrary, until about the turn of the century. [...