The assay of hexokinase activity of the erythrocyte.

The metabolism of the mature mammalian erythrocyte can be considered anomalous in relation to most types of somatic cells, including those from which the erythrocyte is derived. Erythropoiesis takes place mainly in the bone marrow, and is presumed to occur in the following stages: stem blast cell- erythroblast - normoblast - reticulocyte - erythrocyte. The cells up to and including the normoblast stage have a well defined nucleus, whereas the reticulocyte contains only stainable granules believed to be ribonucleoprotein. The mammalian erythrocyte lacks bath the nucleus and stainable granules