Histological study of the proximal convoluted tubule in the developing mouse kidney.

Present knowledge of the fundamental function of the nephron and its role in urine formation and elimination is still incomplete. The nephron bas been subdivided into a standard pattern of segments on the basis of its morphology, and various functions were ascribed to each of the segments through the results of physiological experiments (Richards, 1929). The modern expanded knowledge in the fields of physiology and biochemistry has made it apparent that the conventional segments are further subdivided into zones which divide the labour of urine formation, reabsorption and excretion