the Antidiuretic, Pressor and Oxytocic Properties of Corticotropin-Releasing Factor (CRF).

Since adrenocorticotrophic hormone (ACTH) and cortisone have become of importance for therapeutic use, the factors which regulate the secretion of ACTH have been extensively studied (1). Three views have been put forward concerning this regulation; a) that ACTH secretion is controlled by the systemic blood level of adrenaline; b) that its secretion is controlled and regulated by the systemic blood level of adrenal cortical hormones and; c) it may be controlled by the hypothalamus via the hypophysial portal vessels (1). [...