Vitamin and amino acid interrelationships in the metabolism of a mutant strain of Escherichia coli.

Most strains or Escherichia coli have simple nutritional requirements. This fact indicates that these organisms are able to synthesize all their requirements tor amino acids, purines, pyrimidines, vitamins and other substances necessary for growth in a mixture or a few inorganic salts and glucose. Davis and Mingioli (8), however, have isolated mutant strains or E. coli that require either methionine or vitamin B12 tor growth